UCSD School of Medicine Logo

Peter D. Wagner, M.D.

 

Distinguished Professor of Medicine and Bioengineering

School of Medicine

University of California, San Diego

San Diego, CA  92093-0623A

TEL:  (858) 534-4190

FAX:  (858) 534-4812

E-mail:  pdwagner@ucsd.edu

 

 

EDUCATION

1967           Bachelor of Medical Science (First Class Honors) University of Sydney, Australia

1968           Bachelor of Medicine and Surgery (First Class Honors) University of Sydney, Australia

 

POSTGRADUATE TRAINING

1968           Internship, Professorial Unit, Royal Prince Alfred Hospital, Sydney

1969           Residency, Professorial Unit, Royal Prince Alfred Hospital, Sydney

1970           Postdoctoral Fellowship, University of California, San Diego

 

PROFESSIONAL APPOINTMENTS

1971-72           Postgraduate Research Physiologist, University of California, San Diego

1971-73           Assistant Research Physiologist, University of California, San Diego

1973-78           Assistant Professor of Medicine, University of California, San Diego

1977                Visiting Fellow, Medical Research Council of New Zealand (4/10-5/2)

1978-84           Associate Professor of Medicine, University of California, San Diego

1980-present    Member, Biomedical Sciences Graduate Program, University of California, San Diego

1984-present    Professor of Medicine, University of California, San Diego

1991-present    Member, Institute for Biomedical Engineering, University of California, San Diego

1996-present    Affiliated Faculty, Department of Bioengineering, University of California, San Diego

1999-present    Division Head, Division of Physiology, Department of Medicine, University of California, San Diego

2001-05           Interim Chief, Division of Pulmonary & Critical Care, Department of Medicine, University of California, San Diego

 

SOCIETIES

1971-present    California Thoracic Society

1973-present    American Thoracic Society

1974-present    American Physiological Society

1980-present    American Society for Clinical Investigation

1989-present    International Society on Oxygen Transport to Tissues

1991                Association of American Physicians

1992-  present American College of Sports Medicine

2001                Pulmonary Circulation Foundation

 

CERTIFICATION

1974               American Board of Internal Medicine

1976               Pulmonary Subspecialty Board

 

LICENSURE

1968 - Australia; 1975 - California; 1981 - North Carolina

 

HONORS AND AWARDS

1974-79           NIH Research Career Development Award

1980                American Society for Clinical Investigation

1985-87           ALAC Established Investigator Award

1990                Manuel Tapia Lecturer for 1990 (SEPAR)

1990-91           The Francqui Visiting Professorship (The Free University of Brussels)

1990-2006       Principal Investigator, Program Project (NIH) HL17731

1991                Association of American Physicians

1992                Distinguished Lecturer in Physiology, American College of Chest Physicians

1992-93           President, International Society on Oxygen Transport to Tissues

1994                Faculty Distinguished Lecture, UCSD

1995-96           Chair of Faculty, University of California San Diego School of Medicine

1995-96           Visiting Professor, University of Barcelona, Spain

1996-2006       Principal Investigator, Training Grant (NIH) HL07212

1996-97           European Respiratory Society Teaching Certificate

1996-98           Divisional Representative to the Assembly of the Academic Senate, UCSD

1999                                Honorary Doctorate, University of Barcelona, Spain

2000                                Robert Grover Prize, Pulmonary Circulation Assembly, American Thoracic Society

2001                J. Burns Amberson Award, American Thoracic Society

2001                European Respiratory Society Presidential Award

2002                Edward F. Adolph Distinguished Lectureship Award, Environmental and Exercise Physiology Section, American Physiological Society

2002                Academic Senate Distinguished Teaching Award

2004-05           Principal Investigator, Training Grant (Pulmonary Division) (NIH) HL76126

 

CONSULTANT TO NIH

1975               Cardiovascular-Pulmonary Study Section (ad hoc)

1981               Surgery, Anesthesiology and Trauma Study Section (ad hoc)  

1981-85,90-2  Respiration and Applied Physiology Study Section

1985-87          Respiration and Applied Physiology Study Section (Chair)

1985-87          Special Study Section/site visit (Chair)

1992-96          NIH Health Reviewers Reserve (member)

2000-01          NIH Muscle Biology Work Group (member)

2004               NIH COPD Clinical Research Network (CCRN) Protocol Review Committee (Chair)

2006-pres        NIH Strategic Planning Executive Committee

 

CONSULTANT TO OTHER ORGANIZATIONS

1981               Medical Research Council of Canada

1982               National Health and Medical Research Panel (Australia)

1983               Medical Research Council of New Zealand

1985               VA Research Grant Review

1986               National Science Foundation

1988               National Sciences and Engineering Research Council of Canada

1993                Fonds National de la Recherche Scientifique, Bruxelles, Belgium

1994                The Israel Science Foundation

 

UNIVERSITY COMMITTEES

1978-80          Physiology/Pharmacology Admissions Committee (Chair)

1981-84          Physiology/Pharmacology Minor Proposition Committee (Chair) 

1982-84          Physiology/Pharmacology Graduate Program (Chair)

1982-present   Academic Personnel, Promotional Ad Hoc Committees

1983-84          Council of Chairs, School of Medicine

1984-85           Department of Medicine Committee to Review Appointments in the Research and Adjunct Series (Chair)

1984-85          School of Medicine Standing and Promotions Committee

1984-85          Graduate Program, Admissions Committee

1984-present    Graduate Program, Core Committee

1986-90          Education Committee, Department of Medicine

1987-88          Acting Vice-Chairman, Physiology/Pharmacology Graduate Program (7/1/87-6/30/88)

1987-89           School of Medicine Computing Advisory Committee (Chair)

1989                School of Medicine Staff Appreciation Committee

1989-90           Standing, Promotions and Advisory Committee of the Physiology/Pharmacology Graduate Program

1989-98           Introduction to Clinical Medicine Course Committee (Chair)

1990                Scientific Advisory Committee, Department of Medicine

1990-95           School of Medicine Committee on Educational Policy (Vice-Chair, 1994)

1990                Search Committee for Tasch Endowed Chair in Cancer Research

1991-96           Department of Medicine Committee on Academic Personnel

1992-93           Biomedical Sciences Core Committee

1992-present    Biomedical Sciences Steering Committee

1988-95           School of Medicine Core Curriculum Committee (Chair, 1990-96)

1994-present    Faculty Council (Vice-Chair 1994; Chair 1995)

1995                Institutional Self Study Examination, Curriculum Committee (Chair)

1995-present    Member, Minor Proposition Committee, Biomedical Sciences Graduate Program

1996                Executive Committee, Task Forces for Curricular Review (Chair)

1997-00           Health Sciences Education Subcommittee of Systemwide Academic Senate

1997-00           Academic Senate Division Representative to Senate Assembly

1997-99           UCSD School of Medicine Strategic Planning Committee

1997-98           Chair, Education Task Force, UCSD School of Medicine Strategic Planning Committee

1999                Research Committee, Pulmonary & Critical Care Medicine Division

2000                                Medical Education Center Program Task Force

2000-01           School of Medicine Subcommittee on Research

2000                Chair, School of Medicine Student Evaluation Systems Task Force

2001-02           Vice Chair, Conflict of Interest Management Subcommittee, Independent Review Committee on Conflict of Interest

2001-02           Health Sciences Subcommittee on Research, Academic Senate

2001                Industrial Advisory Board, Whitaker Institute of Biomedical Engineering

2001-04           Core Curriculum Committee, UCSD School of Medicine

2001-03           Brainstorming Group, Dean’s Office, School of Medicine

2002                Liaison Committee on Medical Education (LCME) Task Force Subcommittee on Curriculum

2002-06           Independent Review Committee (IRC) on Conflict of Interest

2002-03           Committee on Distinguished Teaching, Academic Senate

2002-04           Advisory Committee for Center for Functional Magnetic Resonance Imaging

2003                Chair, Pathology Chair Search Committee

2003-04           Pulmonary Chair Search Committee

2003-04           Vice Chair, Committee on Distinguished Teaching, Academic Senate

 

EXTERNAL COMMITTEES

1976-84        Research Subcommittee of the California Research and Medical Education Fund

                     (Chair, 1979-1984)

1984-88        Respiration Section of APS (Secretary-Treasurer)

1984-88        Administrative Committee of the California Research and Medical Education Fund

1985-90      ALA/ATS Research Review Committee (Chair, 1987-1990)

1986-90        ALA Research Coordinating Committee (Member)

1989-91        American Physiological Society (Council Member)

1988-92        Council of Scientific Advisors of the Parker B. Francis Foundation

1990-92        1992 APS Fall Specialty Meeting on Exercise Physiology (Organizer)

1992-93        Awards Committee, American Thoracic Society (Member)

1993-95        ALA/ATS Scientific Advisory Council (Member)

1993-95        American College of Sports Medicine Ad Hoc Basic Science Specialty Conferences Committee (Member)

1994-96        Awards Committee, American Thoracic Society (Chair)

1995-96        Research Task Force, American College of Sports Medicine (Member)

1998-00        Pathophysiology Task Force, National Board of Medical Examiners

1999-2001    Long Range Planning Committee, Respiratory Structure & Function Assembly, American Thoracic Society (Assembly Chair, 2000-01)

2000-pres     Chair, Respiratory Structure & Function Assembly, American Thoracic Society

2000-pres     Board of Directors, American Thoracic Society

2000-03        Program Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2000-02        Publications Policy Committee, American Thoracic Society

2000-02        Advisory Group, Publications Policy Committee, American Thoracic Society

2000             Advisory Group, Proficiency Standards Committee, American Thoracic Society

2000             Assembly Structure Task Force, Board of Directors, American Thoracic Society

2001-03        Planning Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2001-03        Awards Committee, American Thoracic Society

2002-05        Local Arrangements Committee, International Union of Physiological Sciences (IUPS) Congress 2005, American Physiological Society

2002-03        Secretary-Treasurer, American Thoracic Society (2003-4 Vice Pres; 2004-5 Pres-Elect, 2005-6 President)

2002-03        Bioterrorism Task Force, American Thoracic Society

2002-04        Audit and Finance Committee, American Thoracic Society

2002-03        Membership Committee, American Thoracic Society

2002-05        Program and Budget Committee, American Thoracic Society

2003-07        Chair, Financial Committee, American Physiological Society

2003-05        Respiration Section, International Union of Physiological Sciences (IUPS) Commission II

2003-04        Centennial Campaign Planning Subcommittee, American Thoracic Society

2003-04        Planning Committee, American Thoracic Society

2003-08        Chair, Protocol Review Committee, COPD Clinical Research Network, NIH

2003-04        Vice President, American Thoracic Society

2004-05        Chairman, Audit and Finance Committee, American Thoracic Society

2004-05        President-Elect, American Thoracic Society

2005-06        Planning Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2005-06        President, American Thoracic Society

2006-07        Past President, American Thoracic Society

2007             Financial Task Force, American Physiological Society

 

EDITORIAL BOARDS

1976-96, 2005-08        Journal of Applied Physiology

1982-pres                    Respiration Physiology & Neurobiology

1983-92                       International Journal of Clinical Monitoring and Computing

1992-97                       Journal of Clinical Investigation (Associate Editor)

1994-pres                    Archivos de Bronconeumologia (Spanish Society of Pneumology and Thoracic Surgery)

1996-99                       Journal of Critical Care

1998-pres                    American Journal of Respiratory & Critical Care Medicine

1996-2005                   Journal of Applied Physiology (Associate Editor)

1999-pres                    High Altitude Medicine & Biology (Associate Editor)

2006                            US Respiratory Disease Advisory Panel

2006-08                       Physiology in Medicine (PIM) Series, Annals of Internal Medicine (Associate Editor)

2004-pres                    BioMed Central Physiology

 

JOURNALS - GUEST REVIEWER

American Review of Respiratory Disease (1975-93); Journal of Clinical Investigation (1975-); Journal of Morphology (1980-); Chest (1980-); Journal of Allergy & Clinical Immunology (1980-); Arthritis & Rheumatism (1981-); Lung (1982-); Science (1983-); Clinical Respiratory Physiology (1983-); Medical Physics (1983-); Pflugers Archiv (1984-); Experimental Lung Research (1984-); New England Journal of Medicine (1984-); Medical & Biological Engineering & Computing (1984-); Anesthesiology (1986-); European Respiratory Journal (1987-); Canadian Journal of Physiology & Pharmacology (1987-); Pediatric Pulmonology (1988-); IEEE Transactions on Biomedical Engineering (1988-); Medical & Biological Engineering & Computing (1988-1992); Circulation (1989-); Circulation Research (1990-); News in Physiological Sciences (1992-); Bulletin of Mathematical Biology (1992-); Medicine and Science in Sports Exercise (1992-); Journal of Physical Chemistry (1994-); American Journal of Respiratory and Critical Care Medicine (1994-); New England Journal of Medicine (1994-); Coronary Artery Disease (1996-); Annals for Biomedical Engineering (1996-); Medical Engineering & Physics (1996-); Science (2001-); Journal of Cardiac Failure (2003-)

 

Articles

 

1.         1966    Morris, J.S., B.D. Doust, N. Smitananda, P.D. Wagner and J. McRae.  Lung scanning: Technique and some diagnostic uses.  Australian Radiology 10:17-38.

 

2.         1967    Wagner, P.D., J. McRae and J. Read.  Stratified distribution of blood flow in the secondary lobule of the lung.  J. Appl. Physiol. 22:1115-1123.

 

3.         1971    Wagner, P.D., R.W. Mazzone and J.B. West.  Diffusing capacity and anatomic dead space for carbon monoxide (C180).  J. Appl. Physiol. 31:847-852.

 

4.         1972    Wagner, P.D. and J. B. West.  Effects of diffusion impairment on O2 and CO2 time courses in pulmonary capillaries.  J. Appl. Physiol. 33:62-71.

 

5.         1972    Denison, D.M., P.D. Wagner, L. Kingaby and J.B. West.  Cardiorespiratory responses to exercise in air and underwater.  J. Appl. Physiol. 33:426-430.

 

6.         1974    Wagner, P.D., R.B. Laravuso, R.R. Uhl and J.B. West.  Distributions of ventilation/perfusion ratios in acute respiratory failure.  Chest 65:32-35S.

 

7.         1974    Evans, J.W., P.D. Wagner and J.B. West.  Conditions for reduction of pulmonary gas transfer by ventilation/perfusion ratios: theory.  J. Appl. Physiol. 36:533-538.

 

8.         1974    Wagner, P.D., H.A. Saltzman and J.B. West.  Measurement of continuous distributions of ventilation/perfusion ratios: theory.  J. Appl. Physiol. 36:588-599.

 

9.         1974    Wagner, P.D., P.F. Naumann and R.B. Laravuso.  Simultaneous measurement of eight foreign gases in blood by gas chromatography.  J. Appl. Physiol. 36:600-605.

 

10.       1974    Wagner, P.D., R.B. Laravuso, R.R. Uhl and J.B. West.  Continuous distributions of ventilation/perfusion ratios in normal subjects breathing air and 100% O2.  J. Clin. Invest. 54:54-68.

 

11.       1974    West, J.B., P.D. Wagner and C.M.W. Derks.  Gas exchange in distributions of V. a/Q.  ratios: partial pressure solubility diagram.  J. Appl. Physiol. 37:533-540.

 

12.       1974    Wagner, P.D.  The oxyhemoglobin dissociation curve and pulmonary gas exchange.  Seminars in Hematology 11:405-421.

 

13.       1975    Wagner, P.D., R.B. Laravuso, E. Goldzimmer, P.F. Nauman and J.B. West. Distributions of ventilation/perfusion ratios in dogs with normal and abnormal lungs.  J. Appl. Physiol. 38:1099-1109.

 

14.       1975    Dantzker, D.R., P.D. Wagner and J.B. West.  Instability of lung units with low V. a/Q.  ratios during O2 breathing.  J. Appl. Physiol. 38:886-895.

 

15.       1975    West, J.B., H.J. Guy, R.A. Gaines, P.M. Hill and P.D. Wagner.  Battery of single-breath test for rapid measurement of pulmonary function using a respiratory mass spectrometer.  Pneumonologie 151:258-263.

 

16.       1976    Guy, H.J., R.A. Gaines, P.M. Hill, P.D. Wagner and J.B. West.  Computerized non-invasive tests of lung functions: a flexible approach using mass spectrometry.  Am. Rev. Respir. Dis. 113:737-744.

 

17.       1977    Wagner, P.D.  Diffusion and chemical reaction in pulmonary gas exchange.   Physiol. Rev. 57:257-312.

 

18.       1977    Wagner, P.D., D.R. Dantzker, R. Dueck, J.L. Clausen and J.B. West.  Ventilation/perfusion inequality in chronic obstructive pulmonary disease.  J. Clin. Invest. 59:203-216.

 

19.       1977    Evans, J.W. and P.D. Wagner.  Limits on V. a/Q.  distributions from analysis of experimental inert gas elimination.  J. Appl. Physiol. 42:889-898.

 

20.       1977    Wagner, P.D.  A general approach to evaluation of ventilation/perfusion ratios in normal and abnormal lungs.  The Physiologist 20:18-25.

 

21.       1977    Dueck R., P.D. Wagner and J.B. West.  Effects of PEEP on gas exchange in dogs with normal and edematous lungs.  Anesthesiology 47:359-366.

 

22.       1977    Wagner, P.D. and J.W. Evans.  Conditions for equivalence of gas exchange in series and parallel models of the lung.  Respir. Physiol. 31:117-138.

 

23.       1978    Dantzker, D.R., P.D. Wagner, V.W. Tornabene, N.P. Alazarki and J.B. West.  Gas exchange after pulmonary thromboembolization in dogs.  Circ. Res. 42:92-103.

 

24.       1978    Metcalf, J.F., P.D. Wagner and J.B. West.  Effect of local bronchial obstruction on gas exchange in the dog.  Am. Rev. Respir. Dis. 117:85-95.

 

25.       1978    Dueck, R., M. Rathbun and P.D. Wagner.  Chromatographic analysis of multiple tracer inert gases in the presence of  anesthetic gases.  Anesthesiology 48:49-54.

 

26.       1978    Rubinfeld, A.R., P.D. Wagner and J.B. West.  Gas exchange during acute experimental canine asthma.  Am. Rev. Respir. Dis. 118:525-536.

 

27.       1978    Wagner, P.D., D.R. Dantzker, V.E. Iacovoni, W.C. Tomlin and J.B. West.  Ventilation/perfusion inequality in asymptomatic asthma.  Am. Rev. Respir. Dis. 118:511-524.

 

28.       1979    Young, I.H. and P.D. Wagner.  Effect of intrapulmonary hematocrit maldistribution on O2, CO2 and inert gas exchange.  J. Appl. Physiol. 46:372-380.

 

29.       1979    Hedenstierna, G., F.C. White, R.W. Mazzone and P.D. Wagner.  Redistribution of pulmonary blood flow in the dog with PEEP ventilation.  J. Appl. Physiol. 46(2):278-287.

 

30.       1979    Wagner, P.D.  Information content of the multibreath nitrogen washout.  J. Appl. Physiol. 46:579-587.

 

31.       1979    Allen, D.H., D.A. Mathison, P.D. Wagner, D.M. Arroyave and E.M. Tan.  Mediator release during allergen-induced bronchoconstriction in asthmatic subjects.  Chest (Feb. suppl.) 75(2):235-238.

 

32.       1979    Young, I.H. and P.D. Wagner.  Solubility of inert gases in homogenates of canine lung tissue.  J. Appl. Physiol. 46(6):1207-1210.

 

33.       1979    Wagner, P.D.  Computer-assisted analyses of pulmonary function.  In: Progress in Respiration Research, vol. 11., S. Karger Publ., Basel, pp. 305-316.

 

34.       1979    Tornabene, V., J. Fortune, P.D. Wagner and N. Halasz.  Gas exchange after pulmonary fat embolism in dogs.  J. Thorac. Cardiovasc. Surg. 78(4):589-600.

 

35.       1979    Wagner, P.D.  Susceptibility of different gases to ventilation/perfusion inequality.  J. Appl. Physiol. 46(2):372-386.

 

36.       1979    Fortune, J. and P.D. Wagner. Effects of common dead space on inert gas exchange in mathematical models of the lung. J. Appl. Physiol. 47(4):896-906.

 

37.       1979    Hedenstierna, G., F.C. White and P.D. Wagner.  Spatial distribution of pulmonary blood flow in the dog with PEEP ventilation.  J. Appl. Physiol. 47(5):938-949.

 

38.       1980    Dueck, R., I. Young, J. Clausen and P.D. Wagner.  Altered distribution of pulmonary ventilation and blood flow following induction of inhalational anesthesia.  Anesthesia 52:113-125.

 

39.       1980    Young, I., R.W. Mazzone and P.D. Wagner.  Identification of functional lung unit in the dog by graded vascular embolization.  J. Appl. Physiol. 49(1):132-141.

 

40.       1980    Wagner, P.D.  Ventilation/perfusion relationships.  Ann. Rev. Physiol. 42:235-247.

 

41.       1980    West, J.B. and P.D. Wagner.  Gas exchange in exercise at altitude.  In: Exercise Bioenergetics and Gas Exchange, ed. by P. Cerretelli and B.J. Whipp.  Elsevier/North Holland Biomedical Press, pp. 275-284.

 

42.       1980    West, J.B. and P.D. Wagner.  Predicted gas exchange on the summit of Mt. Everest.  Respir. Physiol. 42:1-16.

 

43.       1980    Wagner, P.D.  Calculation of the distribution of ventilation/perfusion ratios from inert gas elimination data.  In:  Proc. of the Symposium on "Bioengineering Approaches in Pulmonary Physiology: Fundamental Principles", FASEB Annual Meeting, April 16, Anaheim.

 

44.       1980    Wagner, P.D.  Introduction to the Symposium on "Bioengineering Approaches in Physiology: Fundamental Principles".  FASEB Annual Meeting, April 16, Anaheim. (Invited Article)

 

45.       1980    Neuman, T.S., R.G. Spragg, P.D. Wagner and K.M. Moser.  Cardiopulmonary consequences of decompression stress.  Respir. Physiol. 41:143-153.

 

46.       1980    Wagner, P.D.  Role of diffusion impairment in gas exchange.  In: Advances in Physiological Sciences, vol. 10.  Respiration, ed. by I. Hutas and  L.A. Debreczeni.  Proc. of the 28th IUPS, Budapest.  Permagon Press, pp. 647-653.

 

47.       1980    Wagner, P.D.  Physiopathologie des rapports ventilation/perfusion.  Rev. fr. Mal. Resp. 8:481-488.  (Invited Article)

 

48.       1980    Wagner, P.D.  Pathophysiology of V. a/Q. . Rev. fr. Mal. Resp.:59-65.  (Invited Article)

 

49.       1981    Wagner, P.D.  Multiple inert gas techniques: Results in normal subjects and patients.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 245-249.

 

50.       1981    Powell, F.L. and P.D. Wagner.  Inert gas transfer in avian lungs.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 283-284.

 

51.       1981    West, J.B. and P.D. Wagner.  Pulmonary gas exchange at high altitude.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 287-295.

 

52.       1981    Wagner, P.D.  Ventilation/perfusion relationships.  Clin. Physiol. 1:437-451.

 

53.       1981    Wagner, P.D.  Estimation of distributions of ventilation/perfusion ratios.  In:  Annals of Biomedical Engineering, vol. 9, pp. 543-556.

 

54.       1982    Wagner, P.D.  Information content of inert gas elimination techniques.  Bull. Europ. Physiopath. Resp. 18:361-372.

 

55.       1982    Wagner, P.D.  Influence of mixed venous Po2 on diffusion of O2 across the pulmonary blood: gas barrier.  Clin. Physiol. 2:105-115.

 

56.       1982    McEvoy, R.D., N.J.H. Davies, F.L. Mannino, R.J. Prutow, P.T. Schumacker,  P.D. Wagner and J.B. West. Pulmonary gas exchange during high-frequency ventilation.  J. Appl. Physiol. 52(5):1278-1287.

 

57.       1982    Powell, F.L. and P.D. Wagner.  Measurement of continuous distributions of ventilation/perfusion in non-alveolar lungs.  Respir. Physiol. 48(2):219-232.

 

58.       1982    Powell, F.L. and P.D. Wagner. Ventilation/perfusion inequality in avian lungs. Respir. Physiol. 48:233-241.

 

59.       1982    McEvoy, R.D., N.J.H. Davies, G. Hedenstierna, M.T. Hartman, R.G. Spragg and  P.D. Wagner.  Lung mucociliary transport during high-frequency ventilation. Am. Rev. Respir. Dis. 126(3):452-456.

 

60.       1982    Ratner, E.R. and P.D. Wagner.  Resolution of the multiple inert gas method for estimating V. a/Q.  maldistribution.  Respir. Physiol. 49:293-313.

 

61.       1982    Breen, P.H., P.T. Schumacker, G. Hedenstierna, J. Ali, P.D. Wagner and L.D.H. Wood. How does increased cardiac output increase shunt in pulmonary edema?  J. Appl. Physiol. 53(5):1273-1280.

 

62.       1982    Bencowitz, H.Z., P.D. Wagner and J.B. West.  Effect of change in P50 on exercise tolerance at high altitude: a theoretical study.  J. Appl. Physiol. 53(6):1487-1495.

 

63.       1982    Wagner, P.D.  Calculating the distribution of ventilation/perfusion ratios from inert elimination data. Fed. Proc. 41(1):136-139.

 

64.       1983    Fortune, J.B., R.W. Mazzone and P.D. Wagner.  Ventilation/perfusion relationships during hemorrhagic hypotension and reinfusion in the dog.  J. Appl. Physiol. 54(4):1071-1082.

 

65.       1983    Romaldini, H., R. Rodriguez-Roisin, P.D. Wagner and J.B. West.  Enhancement of hypoxic pulmonary vasoconstriction by Almitrine in the dog.  Am. Rev. Respir. Dis. 128(2):288-293.

 

66.       1983    Findley, L.J., A.L. Ries, G.M. Tisi and P.D. Wagner.  Hypoxemia during apnea in normal subjects: mechanisms and impact of lung  volume.  J. Appl. Physiol. 55(6):1777-1783.

 

67.       1984    Romaldini, H., R. Rodriguez-Roisin, F.A. Lopez, T.W. Ziegler, H.Z. Bencowitz and P.D. Wagner.  The mechanisms of arterial hypoxemia during hemodialysis.  Am. Rev. Respir. Dis. 129:780-784.

 

68.       1984    Rodriguez-Roisin, R., H.Z. Bencowitz, M.G. Ziegler and P.D. Wagner. Gas exchange responses to bronchodilators following methacholine challenge in dogs.  Am. Rev. Respir. Dis. 130(4):617-626.

 

69.       1984    Bencowitz, H.Z., M.M. LeWinter and P.D. Wagner. Effect of sodium nitroprusside on ventilation/perfusion mismatching in heart  failure.  JACC 4(5):918-922.

 

70.       1985    Schumacker, P.T., B. Guth, A.J. Suggett, P.D. Wagner and J.B. West.  Effects of transfusion-induced polycythemia on O2 transport during exercise in the  dog.  J. Appl. Physiol. 58(3):749-758.

 

71.       1985    Gale, G.E., J. Torre-Bueno, R.E. Moon, H.A. Saltzman and P.D. Wagner.  Ventilation/perfusion inequality in normal humans during exercise at sea level and simulated altitude.  J. Appl. Physiol. 58(3):978-988.

 

72.       1985    Torre-Bueno, J., P.D. Wagner, H.A. Saltzman, G.E. Gale and R.E. Moon.  Diffusion limitation in normal humans during exercise at sea level and simulated altitude.  J. Appl. Physiol. 58(3):989-995.

 

73.       1985    Wagner, P.D.  Gas exchange in chronic pulmonary disease.  Clinical Physiology 5(Suppl. 3):9-17.

 

74.       1985    Kaiser, K.G., N.J.H. Davies, R. Rodriguez-Roisin, H.Z. Bencowitz and P.D. Wagner.  Efficacy of high-frequency ventilation in presence of extensive ventilation/perfusion  mismatch.  J. Appl. Physiol. 58(3):996-1004.

 

75.       1985    Powell, F.L., F.A. Lopez and P.D. Wagner.  Effects of acetone in heparin on the multiple inert gas elimination technique.  J. Appl. Physiol. 58(4):1143-1147.

 

76.       1985    Wagner, P.D., C.M. Smith, N.J.H. Davies, R.D. McEvoy and G.E. Gale.  Estimation of ventilation/perfusion inequality by inert gas elimination without arterial sampling.  J. Appl. Physiol. 59(2):376-383.

 

77.       1985    Schumacker, P.T., A.J. Suggett, P.D. Wagner and J.B. West.  Role of hemoglobin P50 in O2 transport during normoxic and hypoxic exercise in the dog. J. Appl. Physiol. 59(3):749-757.

 

78.       1986    Hammond, M.D., G.E. Gale, K.S. Kapitan, A. Ries and P.D. Wagner.  Pulmonary gas exchange in humans during exercise at sea level.  J. Appl. Physiol. 60(5):1590-1598.

 

79.       1986    Kapitan, K.S. and P.D. Wagner.  Linear programming analysis of V. a/Q.  distributions: limits on central moments.  J. Appl. Physiol. 60(5):1772-1781.

 

80.       1986    Wagner, P.D., G.E. Gale, R.E. Moon, J. Torr-Bueno, B.W. Stolp and H.A. Saltzman. Pulmonary gas exchange in humans exercising at sea level and simulated altitude.  J. Appl. Physiol. 61(1):260-270.

 

81.       1986    Rodriguez-Roisin, R., J. Roca Torrent and P.D. Wagner.  Clinical interest and therapeutic connotations of the measurement of  ventilation/perfusion V. a/Q.  relationships.  Medicina Interna 4(8):385-415.

 

82.       1986    Rodriguez-Roisin, R., J. Roca Torrent and P.D. Wagner.  Clinical interest and therapeutic connotations of the measurement of  ventilation/perfusion V. a/Q.  relationships.  Medicina Interna 4(9):429-456.

 

83.       1986    Hammond, M.D., G.E. Gale, K.S. Kapitan, A. Ries and P.D. Wagner.  Pulmonary gas exchange in humans during normobaric hypoxic exercise.  J. Appl. Physiol. 61(5):1749-1757.

 

84.       1986    Rodriguez-Roisin, R., J. Roca, R. Guitart, AGN Agusti, A. Torres and P.D. Wagner.  Determinacion de las distribuciones de los cocientes ventilacion-perfusion: tecnica de eliminacion de gases inertes multiples.  Rev. Esp. Fisiol. 42(4):465-482.

 

85.       1987    Wagner, P.D.  The lungs during exercise.  NIPS 2:1-10.  (Invited Review)

 

86.       1987    Boynton, B.R., M.D. Hammond, C.A. Hirshman and P.D. Wagner.  The deleterious effect of FPL 55712 on gas exchange in the Basenji-Greyhound dog model in of asthma.  J. Crit. Care 2(1):27-35.

 

87.       1987    Rodriguez-Roisin, J. Roca, AGN Agusti, R. Mastai, P.D. Wagner and J. Bosch.  Gas exchange and pulmonary vascular reactivity in patients with liver cirrhosis.  Am. Rev. Respir. Dis. 135:1085-1092.

 

88.       1987    Wagner, P.D.  Mechanisms of hypoxemia in pulmonary embolism.  Applied Cardiopulmonary Pathophysiology 1:63-71.

 

89.       1987    Kapitan, K.S. and P.D. Wagner.  Linear programming analysis of V. a/Q.  distributions: average distribution.  J. Appl. Physiol. 62(4):1356-1362.

 

90.       1987    Wagner, P.D., G. Hedenstierna, G. Bylin and L. Lagerstrand.  Reproducibility of the multiple inert gas elimination technique.  J. Appl. Physiol. 62(4):1740-1746.

 

91.       1987    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young, J.K. Alexander and C.S. Houston.  Oxygen transport during exercise at extreme altitude: Operation Everest II.  Ann. Emerg. Med. l6:993-998.  (Special Contribution)

 

92.       1987    Groves, B.M., J.T. Reeves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young and C.S. Houston.  Operation Everest II: elevated high-altitude pulmonary resistance unresponsive to oxygen.  J. Appl. Physiol. 63(2):52l-530.

 

93.       1987    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K. Malconian, P.B. Rock, P.M. Young and C.S. Houston.   Operation Everest II: preservation of cardiac function at extreme altitude.  J. Appl. Physiol. 63(2):53l-539.

 

94.       1987    Kapitan, K.S. and P.D. Wagner.  Information content of multiple inert gas elimination measurements.  J. Appl. Physiol. 63(2):86l-868.

 

95.       1987    Wagner, P.D., G. Hedenstierna and G. Bylin.  Ventilation/perfusion inequality in chronic asthma.  Am. Rev. Respir. Dis. l36:605-6l2.

 

96.       1987    Bylin, G., G. Hedenstierna, L. Lagerstrand and P.D. Wagner.  No influence of acetylcysteine on gas exchange and spirometry in chronic asthma.  Eur. J. Respir. Dis. 7l:l02-l07.

 

97.       1987    Roca, J., J.M. Montserrat, R. Rodriguez-Roisin, R. Guitart, A. Torres, AGN  Agusti and P.D. Wagner.  Gas exchange response to naloxone in chronic obstructive pulmonary disease with  hypercapnic respiratory failure.  Bull. Eur. Physiopathol. Respir. 23:249-254.

 

98.       1987    Wagner, P.D., J.R. Sutton, J.T. Reeves, A. Cymerman, B.M. Groves and M.K. Malconian.  Operation Everest II: pulmonary gas exchange during a simulated ascent of Mt.  Everest.  J. Appl. Physiol. 63(6):2348-2359.

 

99.       1988    Roca, J., L.I. Ramis, R. Rodriguez-Roisin, E. Ballester, J.M. Montserrat and P.D. Wagner.  Serial relationships between ventilation/perfusion inequality and spirometry in acute severe asthma requiring hospitalization.  Am. Rev. Respir. Dis. 137:1055-1061.

 

100.     1988    Reyes, A., J. Roca, R. Rodriguez-Roisin, A. Torres, P. Ussetti and P.D. Wagner.  Effect of Almitrine on ventilation/perfusion distribution in Adult Distress Syndrome.  Am. Rev. Respir. Dis. 137:1062-1067.

 

101.     1988    Sutton, J.R., J.T. Reeves, P.D. Wagner, B.M. Groves, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young, S.D. Walter and C.S. Houston.  Operation Everest II: oxygen transport during exercise at extreme simulated altitude.  J. Appl. Physiol. 64(4):1309-1321.

 

102.     1988    Hogan, M.C., J. Roca, P.D. Wagner and J.B. West.  Limitation of maximal O2 uptake and performance by acute hypoxia in dog muscle in situ.  J. Appl. Physiol. 65(2):815-821.

 

103.     1988    Bender, P.R., B.M. Groves, R.E. McCullough, R.G. McCullough, S-Y. Huang, A.J. Hamilton, P.D. Wagner, A. Cymerman and J.T. Reeves.  Oxygen transport to exercising leg in chronic hypoxia.  J. Appl. Physiol. 65(6):2592-2597.

 

104.     1988    Landgren, G.L., J.R. Gillespie, M.R. Fedde, B.W. Jones, R.L. Pieschl and P.D. Wagner.  O2 transport in the horse during rest and exercise.  Adv. Exp. Med. Biol. 227:333-336.

 

105.     1988    Wagner, P.D.  A comparison of man and horse during heavy exercise.  AESM Quarterly 3(4):3-10.

 

106.     1989    Agusti, AGN, J. Roca, R. Rodriguez-Roisin, R. Mastai, P.D. Wagner and J. Bosch.  Pulmonary hemodynamics and gas exchange during exercise in liver cirrhosis.  Am. Rev. Respir. Dis. 139:485-491.

 

107.     1989    Hogan, M.C., J. Roca, J.B. West and P.D. Wagner.  Dissociation of maximal O2 uptake from O2 delivery in canine gastrocnemius in situ.  J. Appl. Physiol. 66(3):1219-1226.

 

108.     1989    Wagner, P.D., J.R. Gillespie. G.L. Landgren, M.F. Fedde, B.W. Jones, R.M. DeBowes, R.L. Pieschl and H.H. Erickson.  Mechanism of exercise-induced hypoxemia in horses.  J. Appl. Physiol. 66(3):1227-1233.

 

109.     1989    Rodriguez-Roisin, R., E. Ballester, J. Roca, A. Torres and P.D. Wagner.  Mechanisms of hypoxemia in patients with status asthmaticus requiring mechanical  ventilation.  Am. Rev. Respir. Dis. 139:732-739.

 

110.     1989    Ballester, E., A. Reyes, J. Roca, R. Guitart, P.D. Wagner and R. Rodriguez-Roisin.  Ventilation/perfusion mismatching in acute severe asthma: effects of salbutamol and 100% oxygen.  Thorax 44:258-267.

 

111.     1989    Kapitan, K.S., M. Buchbinder, P.D. Wagner and K.M. Moser.  Mechanisms of hypoxemia in chronic thromboembolic pulmonary hypertension.  Am. Rev. Respir. Dis. 139:1149-1154.

 

112.     1989    Wagner, P.D., O. Mathieu-Costello, D.E. Bebout, A.T. Gray, P.D. Natterson and C. Glennow.  Protection against pulmonary O2 toxicity by N-acetylcysteine.  Eur. Respir. J. 2:116-126.

 

113.     1989    Ueno, O., L-N. Lee and P.D. Wagner.  Effect of N-acetylcysteine on gas exchange after methacholine challenge and isoprenaline inhalation in the dog.  Eur. Respir. J. 2:238-246.

 

114.     1989    Cymerman, A., J.T. Reeves, J.R. Sutton, P.B. Rock, B.M. Groves, M.K. Malconian, P.M. Young, P.D. Wagner and C.S. Houston.  Operation Everest II: maximal oxygen uptake at extreme altitude.  J. Appl. Physiol. 66(5):2446-2453.

 

115.     1989    Roca, J., M.C. Hogan, D. Story, D.E. Bebout, P. Haab, R. Gonzalez, O. Ueno and P.D. Wagner.  Evidence for tissue diffusion limitation of V. o2max in normal humans.  J. Appl. Physiol. 67(1):291-299.

 

116.     1989    Lee, Li-Na, O. Ueno, P.D. Wagner and J.B. West.  Pulmonary gas exchange after multiple airway occlusion by beads in the dog.  Am. Rev. Respir. Dis. 140:1216-1221.

 

117.     1989    Bebout, D.E., D. Story, J. Roca, M.C. Hogan, D.C. Poole, R. Gonzalez-Camerena, O. Ueno, P. Haab and P.D. Wagner.  Effects of altitude acclimatization on pulmonary gas exchange during exercise.  J. Appl. Physiol. 67(6):2286-2295.

 

118.     1989    Torres, A., A. Reyes, J. Roca, P.D. Wagner and R. Rodriguez-Roisin.  Ventilation/perfusion mismatching in chronic obstructive pulmonary disease during ventilator weaning.  Am. Rev. Respir. Dis. 140:1246-1250.