Peter D. Wagner, M.D.

Distinguished Professor of Medicine and Bioengineering

School of Medicine

University of California, San Diego

San Diego, CA 92093-0623A

TEL:  (858) 534-4190

FAX:  (858) 534-4812

E-mail:  pdwagner@ucsd.edu

EDUCATION

1967           Bachelor of Medical Science (First Class Honors) University of Sydney, Australia

1968           Bachelor of Medicine and Surgery (First Class Honors) University of Sydney, Australia

POSTGRADUATE TRAINING

1968           Internship, Professorial Unit, Royal Prince Alfred Hospital, Sydney

1969           Residency, Professorial Unit, Royal Prince Alfred Hospital, Sydney

1970           Postdoctoral Fellowship, University of California, San Diego

PROFESSIONAL APPOINTMENTS

1971-72           Postgraduate Research Physiologist, University of California, San Diego

1971-73           Assistant Research Physiologist, University of California, San Diego

1973-78           Assistant Professor of Medicine, University of California, San Diego

1977                Visiting Fellow, Medical Research Council of New Zealand (4/10-5/2)

1978-84           Associate Professor of Medicine, University of California, San Diego

1980-present    Member, Biomedical Sciences Graduate Program, University of California, San Diego

1984-present    Professor of Medicine, University of California, San Diego

1991-present    Member, Institute for Biomedical Engineering, University of California, San Diego

1996-present    Affiliated Faculty, Department of Bioengineering, University of California, San Diego

1999-present    Division Head, Division of Physiology, Department of Medicine, University of California, San Diego

2001-05           Interim Chief, Division of Pulmonary & Critical Care, Department of Medicine, University of California, San Diego

SOCIETIES

1971-present    California Thoracic Society

1973-present    American Thoracic Society

1974-present    American Physiological Society

1980-present    American Society for Clinical Investigation

1989-present    International Society on Oxygen Transport to Tissues

1991                Association of American Physicians

1992-  present American College of Sports Medicine

2001                Pulmonary Circulation Foundation

CERTIFICATION

1974               American Board of Internal Medicine

1976               Pulmonary Subspecialty Board

LICENSURE

1968 - Australia; 1975 - California; 1981 - North Carolina

HONORS AND AWARDS

1974-79           NIH Research Career Development Award

1980                American Society for Clinical Investigation

1985-87           ALAC Established Investigator Award

1990                Manuel Tapia Lecturer for 1990 (SEPAR)

1990-91           The Francqui Visiting Professorship (The Free University of Brussels)

1990-2006       Principal Investigator, Program Project (NIH) HL17731

1991                Association of American Physicians

1992                Distinguished Lecturer in Physiology, American College of Chest Physicians

1992-93           President, International Society on Oxygen Transport to Tissues

1994                Faculty Distinguished Lecture, UCSD

1995-96           Chair of Faculty, University of California San Diego School of Medicine

1995-96           Visiting Professor, University of Barcelona, Spain

1996-2006       Principal Investigator, Training Grant (NIH) HL07212

1996-97           European Respiratory Society Teaching Certificate

1996-98           Divisional Representative to the Assembly of the Academic Senate, UCSD

1999 Honorary Doctorate, University of Barcelona, Spain

2000 Robert Grover Prize, Pulmonary Circulation Assembly, American Thoracic Society

2001                J. Burns Amberson Award, American Thoracic Society

2001                European Respiratory Society Presidential Award

2002                Edward F. Adolph Distinguished Lectureship Award, Environmental and Exercise Physiology Section, American Physiological Society

2002                Academic Senate Distinguished Teaching Award

2004-05           Principal Investigator, Training Grant (Pulmonary Division) (NIH) HL76126

CONSULTANT TO NIH

1975               Cardiovascular-Pulmonary Study Section (ad hoc)

1981               Surgery, Anesthesiology and Trauma Study Section (ad hoc)  

1981-85,90-2  Respiration and Applied Physiology Study Section

1985-87          Respiration and Applied Physiology Study Section (Chair)

1985-87          Special Study Section/site visit (Chair)

1992-96          NIH Health Reviewers Reserve (member)

2000-01          NIH Muscle Biology Work Group (member)

2004               NIH COPD Clinical Research Network (CCRN) Protocol Review Committee (Chair)

2006-pres        NIH Strategic Planning Executive Committee

CONSULTANT TO OTHER ORGANIZATIONS

1981               Medical Research Council of Canada

1982               National Health and Medical Research Panel (Australia)

1983               Medical Research Council of New Zealand

1985               VA Research Grant Review

1986               National Science Foundation

1988               National Sciences and Engineering Research Council of Canada

1993                Fonds National de la Recherche Scientifique, Bruxelles, Belgium

1994                The Israel Science Foundation

UNIVERSITY COMMITTEES

1978-80          Physiology/Pharmacology Admissions Committee (Chair)

1981-84          Physiology/Pharmacology Minor Proposition Committee (Chair) 

1982-84          Physiology/Pharmacology Graduate Program (Chair)

1982-present   Academic Personnel, Promotional Ad Hoc Committees

1983-84          Council of Chairs, School of Medicine

1984-85           Department of Medicine Committee to Review Appointments in the Research and Adjunct Series (Chair)

1984-85          School of Medicine Standing and Promotions Committee

1984-85          Graduate Program, Admissions Committee

1984-present    Graduate Program, Core Committee

1986-90          Education Committee, Department of Medicine

1987-88          Acting Vice-Chairman, Physiology/Pharmacology Graduate Program (7/1/87-6/30/88)

1987-89           School of Medicine Computing Advisory Committee (Chair)

1989                School of Medicine Staff Appreciation Committee

1989-90           Standing, Promotions and Advisory Committee of the Physiology/Pharmacology Graduate Program

1989-98           Introduction to Clinical Medicine Course Committee (Chair)

1990                Scientific Advisory Committee, Department of Medicine

1990-95           School of Medicine Committee on Educational Policy (Vice-Chair, 1994)

1990                Search Committee for Tasch Endowed Chair in Cancer Research

1991-96           Department of Medicine Committee on Academic Personnel

1992-93           Biomedical Sciences Core Committee

1992-present    Biomedical Sciences Steering Committee

1988-95           School of Medicine Core Curriculum Committee (Chair, 1990-96)

1994-present    Faculty Council (Vice-Chair 1994; Chair 1995)

1995                Institutional Self Study Examination, Curriculum Committee (Chair)

1995-present    Member, Minor Proposition Committee, Biomedical Sciences Graduate Program

1996                Executive Committee, Task Forces for Curricular Review (Chair)

1997-00           Health Sciences Education Subcommittee of Systemwide Academic Senate

1997-00           Academic Senate Division Representative to Senate Assembly

1997-99           UCSD School of Medicine Strategic Planning Committee

1997-98           Chair, Education Task Force, UCSD School of Medicine Strategic Planning Committee

1999                Research Committee, Pulmonary & Critical Care Medicine Division

2000 Medical Education Center Program Task Force

2000-01           School of Medicine Subcommittee on Research

2000                Chair, School of Medicine Student Evaluation Systems Task Force

2001-02           Vice Chair, Conflict of Interest Management Subcommittee, Independent Review Committee on Conflict of Interest

2001-02           Health Sciences Subcommittee on Research, Academic Senate

2001                Industrial Advisory Board, Whitaker Institute of Biomedical Engineering

2001-04           Core Curriculum Committee, UCSD School of Medicine

2001-03           Brainstorming Group, Dean’s Office, School of Medicine

2002                Liaison Committee on Medical Education (LCME) Task Force Subcommittee on Curriculum

2002-06           Independent Review Committee (IRC) on Conflict of Interest

2002-03           Committee on Distinguished Teaching, Academic Senate

2002-04           Advisory Committee for Center for Functional Magnetic Resonance Imaging

2003                Chair, Pathology Chair Search Committee

2003-04           Pulmonary Chair Search Committee

2003-04           Vice Chair, Committee on Distinguished Teaching, Academic Senate

EXTERNAL COMMITTEES

1976-84        Research Subcommittee of the California Research and Medical Education Fund

                     (Chair, 1979-1984)

1984-88        Respiration Section of APS (Secretary-Treasurer)

1984-88        Administrative Committee of the California Research and Medical Education Fund

1985-90      ALA/ATS Research Review Committee (Chair, 1987-1990)

1986-90        ALA Research Coordinating Committee (Member)

1989-91        American Physiological Society (Council Member)

1988-92        Council of Scientific Advisors of the Parker B. Francis Foundation

1990-92        1992 APS Fall Specialty Meeting on Exercise Physiology (Organizer)

1992-93        Awards Committee, American Thoracic Society (Member)

1993-95        ALA/ATS Scientific Advisory Council (Member)

1993-95        American College of Sports Medicine Ad Hoc Basic Science Specialty Conferences Committee (Member)

1994-96        Awards Committee, American Thoracic Society (Chair)

1995-96        Research Task Force, American College of Sports Medicine (Member)

1998-00        Pathophysiology Task Force, National Board of Medical Examiners

1999-2001    Long Range Planning Committee, Respiratory Structure & Function Assembly, American Thoracic Society (Assembly Chair, 2000-01)

2000-pres     Chair, Respiratory Structure & Function Assembly, American Thoracic Society

2000-pres     Board of Directors, American Thoracic Society

2000-03        Program Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2000-02        Publications Policy Committee, American Thoracic Society

2000-02        Advisory Group, Publications Policy Committee, American Thoracic Society

2000             Advisory Group, Proficiency Standards Committee, American Thoracic Society

2000             Assembly Structure Task Force, Board of Directors, American Thoracic Society

2001-03        Planning Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2001-03        Awards Committee, American Thoracic Society

2002-05        Local Arrangements Committee, International Union of Physiological Sciences (IUPS) Congress 2005, American Physiological Society

2002-03        Secretary-Treasurer, American Thoracic Society (2003-4 Vice Pres; 2004-5 Pres-Elect, 2005-6 President)

2002-03        Bioterrorism Task Force, American Thoracic Society

2002-04        Audit and Finance Committee, American Thoracic Society

2002-03        Membership Committee, American Thoracic Society

2002-05        Program and Budget Committee, American Thoracic Society

2003-07        Chair, Financial Committee, American Physiological Society

2003-05        Respiration Section, International Union of Physiological Sciences (IUPS) Commission II

2003-04        Centennial Campaign Planning Subcommittee, American Thoracic Society

2003-04        Planning Committee, American Thoracic Society

2003-08        Chair, Protocol Review Committee, COPD Clinical Research Network, NIH

2003-04        Vice President, American Thoracic Society

2004-05        Chairman, Audit and Finance Committee, American Thoracic Society

2004-05        President-Elect, American Thoracic Society

2005-06        Planning Committee, Respiratory Structure & Function Assembly, Am. Thor. Soc.

2005-06        President, American Thoracic Society

2006-07        Past President, American Thoracic Society

2007             Financial Task Force, American Physiological Society

EDITORIAL BOARDS

1976-96, 2005-08        Journal of Applied Physiology

1982-pres                    Respiration Physiology & Neurobiology

1983-92                       International Journal of Clinical Monitoring and Computing

1992-97                       Journal of Clinical Investigation (Associate Editor)

1994-pres                    Archivos de Bronconeumologia (Spanish Society of Pneumology and Thoracic Surgery)

1996-99                       Journal of Critical Care

1998-pres                    American Journal of Respiratory & Critical Care Medicine

1996-2005                   Journal of Applied Physiology (Associate Editor)

1999-pres                    High Altitude Medicine & Biology (Associate Editor)

2006                            US Respiratory Disease Advisory Panel

2006-08                       Physiology in Medicine (PIM) Series, Annals of Internal Medicine (Associate Editor)

2004-pres                    BioMed Central Physiology

JOURNALS - GUEST REVIEWER

American Review of Respiratory Disease (1975-93); Journal of Clinical Investigation (1975-); Journal of Morphology (1980-); Chest (1980-); Journal of Allergy & Clinical Immunology (1980-); Arthritis & Rheumatism (1981-); Lung (1982-); Science (1983-); Clinical Respiratory Physiology (1983-); Medical Physics (1983-); Pflugers Archiv (1984-); Experimental Lung Research (1984-); New England Journal of Medicine (1984-); Medical & Biological Engineering & Computing (1984-); Anesthesiology (1986-); European Respiratory Journal (1987-); Canadian Journal of Physiology & Pharmacology (1987-); Pediatric Pulmonology (1988-); IEEE Transactions on Biomedical Engineering (1988-); Medical & Biological Engineering & Computing (1988-1992); Circulation (1989-); Circulation Research (1990-); News in Physiological Sciences (1992-); Bulletin of Mathematical Biology (1992-); Medicine and Science in Sports Exercise (1992-); Journal of Physical Chemistry (1994-); American Journal of Respiratory and Critical Care Medicine (1994-); New England Journal of Medicine (1994-); Coronary Artery Disease (1996-); Annals for Biomedical Engineering (1996-); Medical Engineering & Physics (1996-); Science (2001-); Journal of Cardiac Failure (2003-)

Articles

1.         1966    Morris, J.S., B.D. Doust, N. Smitananda, P.D. Wagner and J. McRae.  Lung scanning: Technique and some diagnostic uses.  Australian Radiology 10:17-38.

2.         1967    Wagner, P.D., J. McRae and J. Read.  Stratified distribution of blood flow in the secondary lobule of the lung.  J. Appl. Physiol. 22:1115-1123.

3.         1971    Wagner, P.D., R.W. Mazzone and J.B. West.  Diffusing capacity and anatomic dead space for carbon monoxide (C¹⁸0).  J. Appl. Physiol. 31:847-852.

4.         1972    Wagner, P.D. and J. B. West.  Effects of diffusion impairment on O₂ and CO₂ time courses in pulmonary capillaries.  J. Appl. Physiol. 33:62-71.

5.         1972    Denison, D.M., P.D. Wagner, L. Kingaby and J.B. West.  Cardiorespiratory responses to exercise in air and underwater.  J. Appl. Physiol. 33:426-430.

6.         1974    Wagner, P.D., R.B. Laravuso, R.R. Uhl and J.B. West.  Distributions of ventilation/perfusion ratios in acute respiratory failure.  Chest 65:32-35S.

7.         1974    Evans, J.W., P.D. Wagner and J.B. West.  Conditions for reduction of pulmonary gas transfer by ventilation/perfusion ratios: theory.  J. Appl. Physiol. 36:533-538.

8.         1974    Wagner, P.D., H.A. Saltzman and J.B. West.  Measurement of continuous distributions of ventilation/perfusion ratios: theory.  J. Appl. Physiol. 36:588-599.

9.         1974    Wagner, P.D., P.F. Naumann and R.B. Laravuso.  Simultaneous measurement of eight foreign gases in blood by gas chromatography.  J. Appl. Physiol. 36:600-605.

10.       1974    Wagner, P.D., R.B. Laravuso, R.R. Uhl and J.B. West.  Continuous distributions of ventilation/perfusion ratios in normal subjects breathing air and 100% O₂.  J. Clin. Invest. 54:54-68.

11.       1974    West, J.B., P.D. Wagner and C.M.W. Derks.  Gas exchange in distributions of V^. a/Q^.  ratios: partial pressure solubility diagram.  J. Appl. Physiol. 37:533-540.

12.       1974    Wagner, P.D.  The oxyhemoglobin dissociation curve and pulmonary gas exchange.  Seminars in Hematology 11:405-421.

13.       1975    Wagner, P.D., R.B. Laravuso, E. Goldzimmer, P.F. Nauman and J.B. West. Distributions of ventilation/perfusion ratios in dogs with normal and abnormal lungs.  J. Appl. Physiol. 38:1099-1109.

14.       1975    Dantzker, D.R., P.D. Wagner and J.B. West.  Instability of lung units with low V^. a/Q^.  ratios during O₂ breathing.  J. Appl. Physiol. 38:886-895.

15.       1975    West, J.B., H.J. Guy, R.A. Gaines, P.M. Hill and P.D. Wagner.  Battery of single-breath test for rapid measurement of pulmonary function using a respiratory mass spectrometer.  Pneumonologie 151:258-263.

16.       1976    Guy, H.J., R.A. Gaines, P.M. Hill, P.D. Wagner and J.B. West.  Computerized non-invasive tests of lung functions: a flexible approach using mass spectrometry.  Am. Rev. Respir. Dis. 113:737-744.

17.       1977    Wagner, P.D.  Diffusion and chemical reaction in pulmonary gas exchange.   Physiol. Rev. 57:257-312.

18.       1977    Wagner, P.D., D.R. Dantzker, R. Dueck, J.L. Clausen and J.B. West.  Ventilation/perfusion inequality in chronic obstructive pulmonary disease.  J. Clin. Invest. 59:203-216.

19.       1977    Evans, J.W. and P.D. Wagner.  Limits on V^. a/Q^.  distributions from analysis of experimental inert gas elimination.  J. Appl. Physiol. 42:889-898.

20.       1977    Wagner, P.D.  A general approach to evaluation of ventilation/perfusion ratios in normal and abnormal lungs.  The Physiologist 20:18-25.

21.       1977    Dueck R., P.D. Wagner and J.B. West.  Effects of PEEP on gas exchange in dogs with normal and edematous lungs.  Anesthesiology 47:359-366.

22.       1977    Wagner, P.D. and J.W. Evans.  Conditions for equivalence of gas exchange in series and parallel models of the lung.  Respir. Physiol. 31:117-138.

23.       1978    Dantzker, D.R., P.D. Wagner, V.W. Tornabene, N.P. Alazarki and J.B. West.  Gas exchange after pulmonary thromboembolization in dogs.  Circ. Res. 42:92-103.

24.       1978    Metcalf, J.F., P.D. Wagner and J.B. West.  Effect of local bronchial obstruction on gas exchange in the dog.  Am. Rev. Respir. Dis. 117:85-95.

25.       1978    Dueck, R., M. Rathbun and P.D. Wagner.  Chromatographic analysis of multiple tracer inert gases in the presence of  anesthetic gases.  Anesthesiology 48:49-54.

26.       1978    Rubinfeld, A.R., P.D. Wagner and J.B. West.  Gas exchange during acute experimental canine asthma.  Am. Rev. Respir. Dis. 118:525-536.

27.       1978    Wagner, P.D., D.R. Dantzker, V.E. Iacovoni, W.C. Tomlin and J.B. West.  Ventilation/perfusion inequality in asymptomatic asthma.  Am. Rev. Respir. Dis. 118:511-524.

28.       1979    Young, I.H. and P.D. Wagner.  Effect of intrapulmonary hematocrit maldistribution on O₂, CO₂ and inert gas exchange.  J. Appl. Physiol. 46:372-380.

29.       1979    Hedenstierna, G., F.C. White, R.W. Mazzone and P.D. Wagner.  Redistribution of pulmonary blood flow in the dog with PEEP ventilation.  J. Appl. Physiol. 46(2):278-287.

30.       1979    Wagner, P.D.  Information content of the multibreath nitrogen washout.  J. Appl. Physiol. 46:579-587.

31.       1979    Allen, D.H., D.A. Mathison, P.D. Wagner, D.M. Arroyave and E.M. Tan.  Mediator release during allergen-induced bronchoconstriction in asthmatic subjects.  Chest (Feb. suppl.) 75(2):235-238.

32.       1979    Young, I.H. and P.D. Wagner.  Solubility of inert gases in homogenates of canine lung tissue.  J. Appl. Physiol. 46(6):1207-1210.

33.       1979    Wagner, P.D.  Computer-assisted analyses of pulmonary function.  In: Progress in Respiration Research, vol. 11., S. Karger Publ., Basel, pp. 305-316.

34.       1979    Tornabene, V., J. Fortune, P.D. Wagner and N. Halasz.  Gas exchange after pulmonary fat embolism in dogs.  J. Thorac. Cardiovasc. Surg. 78(4):589-600.

35.       1979    Wagner, P.D.  Susceptibility of different gases to ventilation/perfusion inequality.  J. Appl. Physiol. 46(2):372-386.

36.       1979    Fortune, J. and P.D. Wagner. Effects of common dead space on inert gas exchange in mathematical models of the lung. J. Appl. Physiol. 47(4):896-906.

37.       1979    Hedenstierna, G., F.C. White and P.D. Wagner.  Spatial distribution of pulmonary blood flow in the dog with PEEP ventilation.  J. Appl. Physiol. 47(5):938-949.

38.       1980    Dueck, R., I. Young, J. Clausen and P.D. Wagner.  Altered distribution of pulmonary ventilation and blood flow following induction of inhalational anesthesia.  Anesthesia 52:113-125.

39.       1980    Young, I., R.W. Mazzone and P.D. Wagner.  Identification of functional lung unit in the dog by graded vascular embolization.  J. Appl. Physiol. 49(1):132-141.

40.       1980    Wagner, P.D.  Ventilation/perfusion relationships.  Ann. Rev. Physiol. 42:235-247.

41.       1980    West, J.B. and P.D. Wagner.  Gas exchange in exercise at altitude.  In: Exercise Bioenergetics and Gas Exchange, ed. by P. Cerretelli and B.J. Whipp.  Elsevier/North Holland Biomedical Press, pp. 275-284.

42.       1980    West, J.B. and P.D. Wagner.  Predicted gas exchange on the summit of Mt. Everest.  Respir. Physiol. 42:1-16.

43.       1980    Wagner, P.D.  Calculation of the distribution of ventilation/perfusion ratios from inert gas elimination data.  In:  Proc. of the Symposium on "Bioengineering Approaches in Pulmonary Physiology: Fundamental Principles", FASEB Annual Meeting, April 16, Anaheim.

44.       1980    Wagner, P.D.  Introduction to the Symposium on "Bioengineering Approaches in Physiology: Fundamental Principles".  FASEB Annual Meeting, April 16, Anaheim. (Invited Article)

45.       1980    Neuman, T.S., R.G. Spragg, P.D. Wagner and K.M. Moser.  Cardiopulmonary consequences of decompression stress.  Respir. Physiol. 41:143-153.

46.       1980    Wagner, P.D.  Role of diffusion impairment in gas exchange.  In: Advances in Physiological Sciences, vol. 10.  Respiration, ed. by I. Hutas and  L.A. Debreczeni.  Proc. of the 28th IUPS, Budapest.  Permagon Press, pp. 647-653.

47.       1980    Wagner, P.D.  Physiopathologie des rapports ventilation/perfusion.  Rev. fr. Mal. Resp. 8:481-488.  (Invited Article)

48.       1980    Wagner, P.D.  Pathophysiology of V^. a/Q^. . Rev. fr. Mal. Resp.:59-65.  (Invited Article)

49.       1981    Wagner, P.D.  Multiple inert gas techniques: Results in normal subjects and patients.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 245-249.

50.       1981    Powell, F.L. and P.D. Wagner.  Inert gas transfer in avian lungs.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 283-284.

51.       1981    West, J.B. and P.D. Wagner.  Pulmonary gas exchange at high altitude.  In: Progress in Respiration Research, vol. 16, ed. by J. Piiper and P. Scheid.  S. Karger Publ., Basel, pp. 287-295.

52.       1981    Wagner, P.D.  Ventilation/perfusion relationships.  Clin. Physiol. 1:437-451.

53.       1981    Wagner, P.D.  Estimation of distributions of ventilation/perfusion ratios.  In:  Annals of Biomedical Engineering, vol. 9, pp. 543-556.

54.       1982    Wagner, P.D.  Information content of inert gas elimination techniques.  Bull. Europ. Physiopath. Resp. 18:361-372.

55.       1982    Wagner, P.D.  Influence of mixed venous Po₂ on diffusion of O₂ across the pulmonary blood: gas barrier.  Clin. Physiol. 2:105-115.

56.       1982    McEvoy, R.D., N.J.H. Davies, F.L. Mannino, R.J. Prutow, P.T. Schumacker,  P.D. Wagner and J.B. West. Pulmonary gas exchange during high-frequency ventilation.  J. Appl. Physiol. 52(5):1278-1287.

57.       1982    Powell, F.L. and P.D. Wagner.  Measurement of continuous distributions of ventilation/perfusion in non-alveolar lungs.  Respir. Physiol. 48(2):219-232.

58.       1982    Powell, F.L. and P.D. Wagner. Ventilation/perfusion inequality in avian lungs. Respir. Physiol. 48:233-241.

59.       1982    McEvoy, R.D., N.J.H. Davies, G. Hedenstierna, M.T. Hartman, R.G. Spragg and  P.D. Wagner.  Lung mucociliary transport during high-frequency ventilation. Am. Rev. Respir. Dis. 126(3):452-456.

60.       1982    Ratner, E.R. and P.D. Wagner.  Resolution of the multiple inert gas method for estimating V^. a/Q^.  maldistribution.  Respir. Physiol. 49:293-313.

61.       1982    Breen, P.H., P.T. Schumacker, G. Hedenstierna, J. Ali, P.D. Wagner and L.D.H. Wood. How does increased cardiac output increase shunt in pulmonary edema?  J. Appl. Physiol. 53(5):1273-1280.

62.       1982    Bencowitz, H.Z., P.D. Wagner and J.B. West.  Effect of change in P₅₀ on exercise tolerance at high altitude: a theoretical study.  J. Appl. Physiol. 53(6):1487-1495.

63.       1982    Wagner, P.D.  Calculating the distribution of ventilation/perfusion ratios from inert elimination data. Fed. Proc. 41(1):136-139.

64.       1983    Fortune, J.B., R.W. Mazzone and P.D. Wagner.  Ventilation/perfusion relationships during hemorrhagic hypotension and reinfusion in the dog.  J. Appl. Physiol. 54(4):1071-1082.

65.       1983    Romaldini, H., R. Rodriguez-Roisin, P.D. Wagner and J.B. West.  Enhancement of hypoxic pulmonary vasoconstriction by Almitrine in the dog.  Am. Rev. Respir. Dis. 128(2):288-293.

66.       1983    Findley, L.J., A.L. Ries, G.M. Tisi and P.D. Wagner.  Hypoxemia during apnea in normal subjects: mechanisms and impact of lung  volume.  J. Appl. Physiol. 55(6):1777-1783.

67.       1984    Romaldini, H., R. Rodriguez-Roisin, F.A. Lopez, T.W. Ziegler, H.Z. Bencowitz and P.D. Wagner.  The mechanisms of arterial hypoxemia during hemodialysis.  Am. Rev. Respir. Dis. 129:780-784.

68.       1984    Rodriguez-Roisin, R., H.Z. Bencowitz, M.G. Ziegler and P.D. Wagner. Gas exchange responses to bronchodilators following methacholine challenge in dogs.  Am. Rev. Respir. Dis. 130(4):617-626.

69.       1984    Bencowitz, H.Z., M.M. LeWinter and P.D. Wagner. Effect of sodium nitroprusside on ventilation/perfusion mismatching in heart  failure.  JACC 4(5):918-922.

70.       1985    Schumacker, P.T., B. Guth, A.J. Suggett, P.D. Wagner and J.B. West.  Effects of transfusion-induced polycythemia on O₂ transport during exercise in the  dog.  J. Appl. Physiol. 58(3):749-758.

71.       1985    Gale, G.E., J. Torre-Bueno, R.E. Moon, H.A. Saltzman and P.D. Wagner.  Ventilation/perfusion inequality in normal humans during exercise at sea level and simulated altitude.  J. Appl. Physiol. 58(3):978-988.

72.       1985    Torre-Bueno, J., P.D. Wagner, H.A. Saltzman, G.E. Gale and R.E. Moon.  Diffusion limitation in normal humans during exercise at sea level and simulated altitude.  J. Appl. Physiol. 58(3):989-995.

73.       1985    Wagner, P.D.  Gas exchange in chronic pulmonary disease.  Clinical Physiology 5(Suppl. 3):9-17.

74.       1985    Kaiser, K.G., N.J.H. Davies, R. Rodriguez-Roisin, H.Z. Bencowitz and P.D. Wagner.  Efficacy of high-frequency ventilation in presence of extensive ventilation/perfusion  mismatch.  J. Appl. Physiol. 58(3):996-1004.

75.       1985    Powell, F.L., F.A. Lopez and P.D. Wagner.  Effects of acetone in heparin on the multiple inert gas elimination technique.  J. Appl. Physiol. 58(4):1143-1147.

76.       1985    Wagner, P.D., C.M. Smith, N.J.H. Davies, R.D. McEvoy and G.E. Gale.  Estimation of ventilation/perfusion inequality by inert gas elimination without arterial sampling.  J. Appl. Physiol. 59(2):376-383.

77.       1985    Schumacker, P.T., A.J. Suggett, P.D. Wagner and J.B. West.  Role of hemoglobin P₅₀ in O₂ transport during normoxic and hypoxic exercise in the dog. J. Appl. Physiol. 59(3):749-757.

78.       1986    Hammond, M.D., G.E. Gale, K.S. Kapitan, A. Ries and P.D. Wagner.  Pulmonary gas exchange in humans during exercise at sea level.  J. Appl. Physiol. 60(5):1590-1598.

79.       1986    Kapitan, K.S. and P.D. Wagner.  Linear programming analysis of V^. a/Q^.  distributions: limits on central moments.  J. Appl. Physiol. 60(5):1772-1781.

80.       1986    Wagner, P.D., G.E. Gale, R.E. Moon, J. Torr-Bueno, B.W. Stolp and H.A. Saltzman. Pulmonary gas exchange in humans exercising at sea level and simulated altitude.  J. Appl. Physiol. 61(1):260-270.

81.       1986    Rodriguez-Roisin, R., J. Roca Torrent and P.D. Wagner.  Clinical interest and therapeutic connotations of the measurement of  ventilation/perfusion V^. a/Q^.  relationships.  Medicina Interna 4(8):385-415.

82.       1986    Rodriguez-Roisin, R., J. Roca Torrent and P.D. Wagner.  Clinical interest and therapeutic connotations of the measurement of  ventilation/perfusion V^. a/Q^.  relationships.  Medicina Interna 4(9):429-456.

83.       1986    Hammond, M.D., G.E. Gale, K.S. Kapitan, A. Ries and P.D. Wagner.  Pulmonary gas exchange in humans during normobaric hypoxic exercise.  J. Appl. Physiol. 61(5):1749-1757.

84.       1986    Rodriguez-Roisin, R., J. Roca, R. Guitart, AGN Agusti, A. Torres and P.D. Wagner.  Determinacion de las distribuciones de los cocientes ventilacion-perfusion: tecnica de eliminacion de gases inertes multiples.  Rev. Esp. Fisiol. 42(4):465-482.

85.       1987    Wagner, P.D.  The lungs during exercise.  NIPS 2:1-10.  (Invited Review)

86.       1987    Boynton, B.R., M.D. Hammond, C.A. Hirshman and P.D. Wagner.  The deleterious effect of FPL 55712 on gas exchange in the Basenji-Greyhound dog model in of asthma.  J. Crit. Care 2(1):27-35.

87.       1987    Rodriguez-Roisin, J. Roca, AGN Agusti, R. Mastai, P.D. Wagner and J. Bosch.  Gas exchange and pulmonary vascular reactivity in patients with liver cirrhosis.  Am. Rev. Respir. Dis. 135:1085-1092.

88.       1987    Wagner, P.D.  Mechanisms of hypoxemia in pulmonary embolism.  Applied Cardiopulmonary Pathophysiology 1:63-71.

89.       1987    Kapitan, K.S. and P.D. Wagner.  Linear programming analysis of V^. a/Q^.  distributions: average distribution.  J. Appl. Physiol. 62(4):1356-1362.

90.       1987    Wagner, P.D., G. Hedenstierna, G. Bylin and L. Lagerstrand.  Reproducibility of the multiple inert gas elimination technique.  J. Appl. Physiol. 62(4):1740-1746.

91.       1987    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young, J.K. Alexander and C.S. Houston.  Oxygen transport during exercise at extreme altitude: Operation Everest II.  Ann. Emerg. Med. l6:993-998.  (Special Contribution)

92.       1987    Groves, B.M., J.T. Reeves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young and C.S. Houston.  Operation Everest II: elevated high-altitude pulmonary resistance unresponsive to oxygen.  J. Appl. Physiol. 63(2):52l-530.

93.       1987    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K. Malconian, P.B. Rock, P.M. Young and C.S. Houston.   Operation Everest II: preservation of cardiac function at extreme altitude.  J. Appl. Physiol. 63(2):53l-539.

94.       1987    Kapitan, K.S. and P.D. Wagner.  Information content of multiple inert gas elimination measurements.  J. Appl. Physiol. 63(2):86l-868.

95.       1987    Wagner, P.D., G. Hedenstierna and G. Bylin.  Ventilation/perfusion inequality in chronic asthma.  Am. Rev. Respir. Dis. l36:605-6l2.

96.       1987    Bylin, G., G. Hedenstierna, L. Lagerstrand and P.D. Wagner.  No influence of acetylcysteine on gas exchange and spirometry in chronic asthma.  Eur. J. Respir. Dis. 7l:l02-l07.

97.       1987    Roca, J., J.M. Montserrat, R. Rodriguez-Roisin, R. Guitart, A. Torres, AGN  Agusti and P.D. Wagner.  Gas exchange response to naloxone in chronic obstructive pulmonary disease with  hypercapnic respiratory failure.  Bull. Eur. Physiopathol. Respir. 23:249-254.

98.       1987    Wagner, P.D., J.R. Sutton, J.T. Reeves, A. Cymerman, B.M. Groves and M.K. Malconian.  Operation Everest II: pulmonary gas exchange during a simulated ascent of Mt.  Everest.  J. Appl. Physiol. 63(6):2348-2359.

99.       1988    Roca, J., L.I. Ramis, R. Rodriguez-Roisin, E. Ballester, J.M. Montserrat and P.D. Wagner.  Serial relationships between ventilation/perfusion inequality and spirometry in acute severe asthma requiring hospitalization.  Am. Rev. Respir. Dis. 137:1055-1061.

100.     1988    Reyes, A., J. Roca, R. Rodriguez-Roisin, A. Torres, P. Ussetti and P.D. Wagner.  Effect of Almitrine on ventilation/perfusion distribution in Adult Distress Syndrome.  Am. Rev. Respir. Dis. 137:1062-1067.

101.     1988    Sutton, J.R., J.T. Reeves, P.D. Wagner, B.M. Groves, A. Cymerman, M.K.  Malconian, P.B. Rock, P.M. Young, S.D. Walter and C.S. Houston.  Operation Everest II: oxygen transport during exercise at extreme simulated altitude.  J. Appl. Physiol. 64(4):1309-1321.

102.     1988    Hogan, M.C., J. Roca, P.D. Wagner and J.B. West.  Limitation of maximal O₂ uptake and performance by acute hypoxia in dog muscle in situ.  J. Appl. Physiol. 65(2):815-821.

103.     1988    Bender, P.R., B.M. Groves, R.E. McCullough, R.G. McCullough, S-Y. Huang, A.J. Hamilton, P.D. Wagner, A. Cymerman and J.T. Reeves.  Oxygen transport to exercising leg in chronic hypoxia.  J. Appl. Physiol. 65(6):2592-2597.

104.     1988    Landgren, G.L., J.R. Gillespie, M.R. Fedde, B.W. Jones, R.L. Pieschl and P.D. Wagner.  O₂ transport in the horse during rest and exercise.  Adv. Exp. Med. Biol. 227:333-336.

105.     1988    Wagner, P.D.  A comparison of man and horse during heavy exercise.  AESM Quarterly 3(4):3-10.

106.     1989    Agusti, AGN, J. Roca, R. Rodriguez-Roisin, R. Mastai, P.D. Wagner and J. Bosch.  Pulmonary hemodynamics and gas exchange during exercise in liver cirrhosis.  Am. Rev. Respir. Dis. 139:485-491.

107.     1989    Hogan, M.C., J. Roca, J.B. West and P.D. Wagner.  Dissociation of maximal O₂ uptake from O₂ delivery in canine gastrocnemius in situ.  J. Appl. Physiol. 66(3):1219-1226.

108.     1989    Wagner, P.D., J.R. Gillespie. G.L. Landgren, M.F. Fedde, B.W. Jones, R.M. DeBowes, R.L. Pieschl and H.H. Erickson.  Mechanism of exercise-induced hypoxemia in horses.  J. Appl. Physiol. 66(3):1227-1233.

109.     1989    Rodriguez-Roisin, R., E. Ballester, J. Roca, A. Torres and P.D. Wagner.  Mechanisms of hypoxemia in patients with status asthmaticus requiring mechanical  ventilation.  Am. Rev. Respir. Dis. 139:732-739.

110.     1989    Ballester, E., A. Reyes, J. Roca, R. Guitart, P.D. Wagner and R. Rodriguez-Roisin.  Ventilation/perfusion mismatching in acute severe asthma: effects of salbutamol and 100% oxygen.  Thorax 44:258-267.

111.     1989    Kapitan, K.S., M. Buchbinder, P.D. Wagner and K.M. Moser.  Mechanisms of hypoxemia in chronic thromboembolic pulmonary hypertension.  Am. Rev. Respir. Dis. 139:1149-1154.

112.     1989    Wagner, P.D., O. Mathieu-Costello, D.E. Bebout, A.T. Gray, P.D. Natterson and C. Glennow.  Protection against pulmonary O₂ toxicity by N-acetylcysteine.  Eur. Respir. J. 2:116-126.

113.     1989    Ueno, O., L-N. Lee and P.D. Wagner.  Effect of N-acetylcysteine on gas exchange after methacholine challenge and isoprenaline inhalation in the dog.  Eur. Respir. J. 2:238-246.

114.     1989    Cymerman, A., J.T. Reeves, J.R. Sutton, P.B. Rock, B.M. Groves, M.K. Malconian, P.M. Young, P.D. Wagner and C.S. Houston.  Operation Everest II: maximal oxygen uptake at extreme altitude.  J. Appl. Physiol. 66(5):2446-2453.

115.     1989    Roca, J., M.C. Hogan, D. Story, D.E. Bebout, P. Haab, R. Gonzalez, O. Ueno and P.D. Wagner.  Evidence for tissue diffusion limitation of V^. o₂max in normal humans.  J. Appl. Physiol. 67(1):291-299.

116.     1989    Lee, Li-Na, O. Ueno, P.D. Wagner and J.B. West.  Pulmonary gas exchange after multiple airway occlusion by beads in the dog.  Am. Rev. Respir. Dis. 140:1216-1221.

117.     1989    Bebout, D.E., D. Story, J. Roca, M.C. Hogan, D.C. Poole, R. Gonzalez-Camerena, O. Ueno, P. Haab and P.D. Wagner.  Effects of altitude acclimatization on pulmonary gas exchange during exercise.  J. Appl. Physiol. 67(6):2286-2295.

118.     1989    Torres, A., A. Reyes, J. Roca, P.D. Wagner and R. Rodriguez-Roisin.  Ventilation/perfusion mismatching in chronic obstructive pulmonary disease during ventilator weaning.  Am. Rev. Respir. Dis. 140:1246-1250.

119.     1989    Bender, P.R., R. E. Mc Cullough, R.G. McCullough, S-Y, Huang, P.D. Wagner, A. Cymerman, A.J. Hamilton and J.T. Reeves.  Increased exercise Sao₂ independent of ventilatory acclimatization at 4,300 m.  J. Appl. Physiol. 66(6):2733-2738.

120.     1990    Hsia, C.C.W., J.I. Carlin, P.D. Wagner, S.S. Cassidy and R.L. Johnson Jr.  Gas exchange abnormalities after pneumonectomy in conditioned foxhounds.  J. Appl. Physiol. 68(1):94-104.

121.     1990    Agusti, AGN, J.A. Barberá, J. Roca, P.D. Wagner, R. Guitart and R. Rodriguez-Roisin.  Hypoxic pulmonary vasoconstriction and gas exchange during exercise in chronic obstructive pulmonary disease.  Chest 97:268-275.

122.     1990    Barberá, B.A., J. Ramirez, J. Roca, P.D. Wagner, J. Sanchez-Lloret and R. Rodriguez-Roisin.  Lung structure and gas exchange in mild chronic obstructive pulmonary disease.  Am. Rev. Respir. Dis. 141:895-901.

123.     1990    Ballester, E., J. Roca, L.I. Ramis, P.D. Wagner and R. Rodriguez-Roisin.  Pulmonary gas exchange in severe chronic asthma.  Response to 100% oxygen and salbutamol.  Am. Rev. Respir. Dis. 141:558-562.

124.     1990    Rodriguez-Roisin, R. and P.D. Wagner.  Clinical relevance of ventilation/perfusion inequality determined by inert gas elimination.  Eur. Respir. J. 3:469-482.

125.     1990    Tsukimoto, K., J.P. Arcos, W. Schaffartzik, P.D. Wagner and J.B. West.  Effect of common dead space on V^. a/Q^.  distribution in the dog.  J. Appl. Physiol. 68:2488-2493.

126.     1990    Reeves, J.T., B.M. Groves, A. Cymerman, J.R. Sutton, P.D. Wagner, D. Turkevich and C.S. Houston.  Operation Everest II: cardiac filling pressures during cycle exercise at sea level.  Respir. Physiol. 80:147-154.

127.     1990    Agusti, AGN, J. Roca, J. Bosch, J.C. Garcia-Pagan, P.D. Wagner and R. Rodriguez-Roisin.  Effects of propranolol on arterial oxygenation and oxygen transport to tissues in patients with cirrhosis.  Am. Rev. Respir. Dis. 142:306-310.

128.     1990    Hogan, M.C., D.E. Bebout, P.D. Wagner and J.B. West.  Maximal O₂ uptake of in situ dog muscle during acute hypoxemia with constant perfusion.  J. Appl. Physiol. 69(2):570-576.

129.     1990    Hogan, M.D., D.E. Bebout, A.T. Gray, P.D. Wagner, J.B. West and P.E. Haab.  Muscle maximal O₂ uptake at constant O₂ delivery with and without CO in the blood. J. Appl. Physiol. 69(2):830-836.

130.     1990    Wagner, P.D., J. Roca, M.C. Hogan, D.C. Poole, D.E. Bebout and P. Haab.  Experimental support for the theory of diffusion limitation of maximum oxygen uptake.  In:  Oxygen Transport to Tissue XII, ed. by J. Piiper et al.  Plenum Press, New York, pp. 825-833.

131.     1991    Agusti, AGN, J. Roca, J. Gea, P.D. Wagner, A. Xaubet and R. Rodriguez-Roisin.  Mechanisms of gas-exchange impairment in idiopathic pulmonary fibrosis.  Am. Rev. Respir. Dis. 143(2):219-225.

132.     1991    Wagner, P.D. and R. Rodriguez-Roisin.  Clinical advances in pulmonary gas exchange. Am. Rev. Respir. Dis. 143(4):883-888.

133.     1991    Wagner, P.D.  On writing a grant application: a personal view.  The Physiologist 34(2):29-31.

134.     1991    Hogan, M.C., D.E. Bebout and P.D. Wagner.  Effect of hemoglobin concentration on maximal O₂ uptake in canine gastrocnemius muscle in situ.  J. Appl. Physiol. 70(3):1105-1112.

135.     1991    Hogan, M.C., D.E. Bebout and P.D. Wagner.  Effect of increased Hb-O₂ affinity on V^. o₂max at constant O₂ delivery in dog muscle in situ.  J. Appl. Physiol. 70(6):2656-2662.

136.     1991    Barberá, J.A., J. Roca, J. Ramirez, P.D. Wagner, P. Usetti and R. Rodriguez-Roisin.  Gas exchange during exercise in mild chronic obstructive pulmonary disease: correlation with lung structure.  Am. Rev. Respir. Dis. 144:520-525.

137.     1991    Poole, D.C., W. Schaffartzik, D.R. Knight, T. Derion, B. Kennedy, H.J. Guy, R. Prediletto and P.D. Wagner.  Contribution of exercising legs to the slow component of oxygen uptake kinetics in humans.  J. Appl. Physiol. 71(4):1245-1253.

138.     1991    Rodriguez-Roisin, R., A. Ferrer, D. Navajas, AGN Agusti, P.D. Wagner and J. Roca.  Ventilation/perfusion mismatch after methacholine challenge in patients with mild bronchial asthma.  Am. Rev. Respir. Dis. 144:88-94.

139.     1991    Gea, J., J. Roca, A. Torres, AGN Agusti, P.D. Wagner and R. Rodriguez-Roisin.  Mechanisms of abnormal gas exchange in patients with pneumonia.  Anesthesiology 75(5):782-789.

140.     1991    Wagner, P.D., W. Schaffartzik, R. Prediletto and D.R. Knight.  Relationship among cardiac output, shunt, and inspired O₂ concentration.  J. Appl. Physiol. 71(6):2191-2197.

141.     1992    Wagner, P.D. et al.  NHLBI Workshop Summary -- Hyperbaric Oxygenation Therapy.  Am. Rev. Respir. Dis. 144:1414-1421.

142.     1992    Wagner, P.D.  Gas exchange and peripheral diffusion limitation.  Med. Sci. Sports Exerc. 24(1):54-58.

143.     1992    Derion, T., H.J.B. Guy, K. Tsukimoto, W. Schaffartzik, R. Prediletto, D.C. Poole, D.R. Knight and P.D. Wagner.  Ventilation/perfusion relationships in the lung during head-out water immersion.  J. Appl. Physiol. 72(1):64-72.

144.     1992    Poole, D.C., W. Schaffartzik, D.R. Knight, T. Derion, R. Prediletto, M.Z. Ziegler, H. Guy and P.D. Wagner.  Pulmonary and leg V^. o₂ during submaximal exercise:  implications for muscular efficiency.  J. Appl. Physiol. 72(2):805-810, 1992.

145.     1992    Tsukimoto, K., J.P. Arcos, W. Schaffartzik, P.D. Wagner and J.B. West.  Effects of inspired CO₂, hyperventilation, and time on V^. a/Q^.  inequality in the dog.  J. Appl. Physiol. 72(3):1057-1063, 1992.

146.     1992    Schaffartzik, W., D.C. Poole, T. Derion, K. Tsukimoto, M.C. Hogan, J.P. Arcos, D.E. Bebout and P.D. Wagner.  V^. a/Q^.  distribution during heavy exercise and recovery in humans: implications for pulmonary edema.  J. Appl. Physiol. 72(5):1657-1667, 1992.

147.     1992    Wagner, P.D.  Ventilation/perfusion matching during exercise.  Chest 101(5):192S-198S, 1992.

148.     1992    Barberá, J.A., A. Reyes, J. Roca, J.M. Montserrat, P.D. Wagner and R. Rodriguez-Roisin.  Effect of intravenously administered Aminophylline on ventilation/perfusion inequality during recovery from exacerbations of Chronic Obstructive Pulmonary Disease.  Am. Rev. Respir. Dis. 145:1328-1333, 1992.

149.     1992    Lagerstrand, L., G. Bylin, G. Hedenstierna and P.D. Wagner.  Relationships among gas exchange, spirometry and symptoms in asthma.  Eur. J. Med. 1(3): 145-152, 1992.

150.     1992    Wagner, P.D.  Maximal oxygen consumption.  Nouvelles de la Science et des Technologies 10(1-2):15-19, 1992. (Invited Article)

151.     1992    Hogan, M.C., P.G. Arthur, D.E. Bebout, P.W. Hochachka and P.D. Wagner.  Role of O₂ in regulating tissue respiration in dog muscle working in situ.  J. Appl. Physiol. 73(2):728-736, 1992.

152.     1992    Roca, J., A. GN Agusti, A. Alonso, D.C. Poole, C. Viegas, J.A. Barberá, R. Rodriguez-Roisin, A. Ferrer and P.D. Wagner.  Effects of training on muscle O₂ transport at V^. o₂max.  J. Appl. Physiol. 73(3):1067-1076, 1992.

153.     1992    Knight, D.R., D.C. Poole, W. Schaffartzik, H.J. Guy, R. Prediletto, M.C. Hogan and P.D. Wagner.  Relationship between body and leg V^. o₂ during maximal cycle ergometry.  J. Appl. Physiol. 73(3):1114-1121, 1992.

154.     1992    Arthur, P.G., M.C. Hogan, D.E. Bebout, P.D. Wagner and P.W. Hochachka.  Modeling the effects of hypoxia on ATP turnover in exercising muscle.  J. Appl. Physiol. 73(2):737-742, 1992.

155.     1992    Hogan, M.C., D.C. Willford, P.E. Keipert, N.S. Faithfull and P.D. Wagner.  Increased plasma O₂ solubility improves O₂ uptake of in situ dog muscle working maximally.  J. Appl. Physiol. 73(6):2470-2475, 1992.

156.     1992    Sutton, J.R., J.T. Reeves, B.M. Groves, P.D. Wagner, J.K. Alexander, H.N. Hultgren, A. Cymerman, C.S. Houston.  Oxygen transport and cardiovascular function at extreme altitude: lessons from Operation Everest II.  Intl. J. Sports Med. Oct 13, Suppl 1; S13-S18, 1992.

157.     1993    Hsia, C.C.W., L.F. Herazo, M. Ramanathan, R.L. Johnson, Jr. and P.D. Wagner.  Cardiopulmonary adaptations to pneumonectomy in dogs.  II. V^. a/Q^.  relationships and microvascular recruitment.  J. Appl. Physiol. 74(3):1299-1309, 1993.

158.     1993    Naeije, C. Mélot, G. Niset, M. Delcroix and P.D. Wagner.  Mechanisms of improved arterial oxygenation after peripheral chemoreceptor stimulation during hypoxic exercise.  J. Appl. Physiol. 74(4):1666-1671, 1993.

159.     1993    Bebout, D.E., M.C. Hogan, S.C. Hempleman and P.D. Wagner. Effects of training and immobilization on V^. o₂ and Do₂ in dog gastrocnemius muscle in situ. J. Appl. Physiol. 74(4):1697-1703, 1993.

160.     1993    Hogan, M.C., D.E. Bebout and P.D. Wagner.  Effect of blood flow reduction on maximal O₂ uptake in canine gastrocnemius muscle in situ.  J. Appl. Physiol. 74(4):1742-1747, 1993.

161.     1993    Ferrer, A., J. Roca, P.D. Wagner, F.A. Lopez and R. Rodriguez-Roisin.  Airway obstruction and ventilation/perfusion relationships in acute severe asthma.  Am. Rev. Respir. Dis. 147(3):579-584, 1993.

162.     1993    Wagner, P.D.  Algebraic analysis of the determinants of V^. o₂max.  Respir. Physiol. 93(2):221-237, 1993.

163.     1993    Schaffartzik, W., E.D. Barton, D.C. Poole, K. Tsukimoto, M.C. Hogan, D.E. Bebout and P.D. Wagner.  Effect of reduced hemoglobin concentration on leg oxygen uptake during maximal exercise in humans.  J. Appl. Physiol. 75(2):491-498, 1993.

164.     1993    Gonzalez, N.C., R.L. Clancy, and P.D. Wagner.  Determinants of maximum oxygen uptake in rats acclimated to simulated altitude.  J. Appl. Physiol. 75(4):1608-1614.

165.     1993    Richardson, R.S., D.C. Poole, D.R. Knight, S.S. Kurdak, M.C. Hogan, B. Grassi, E.C. Johnson, K. Kendrick, B.K. Erickson and P.D. Wagner.  High muscle blood flow in man: is maximal O₂ extraction compromised?  J. Appl. Physiol.  75(4):1911-1916, 1993.

166.     1993    Welsh, C.H., P.D. Wagner, J.T. Reeves, D. Lynch, T.M. Cink, J. Armstrong, M.K. Malconian, P.B. Rock and C.S. Houston.  Operation Everest II: spirometric and radiographic changes in acclimatized humans at simulated high altitude.  Am. Rev. Resp. Dis.  147(5):1239-1244, 1993.

167.     1993    Knight, D.R., W. Schaffartzik, D.C. Poole, M.C. Hogan, D.E. Bebout and P.D. Wagner.  Effects of hyperoxia on maximal leg O₂ supply and utilization in man.  J. Appl. Physiol. 75(6):2586-2594, 1993.

168.     1993    Schaffartzik, W., J. Arcos, K. Tsukimoto, O. Mathieu-Costello and P.D. Wagner.  Pulmonary interstitial edema in the pig after heavy exercise.  J. Appl. Physiol. 75(6):2535-2540, 1993.

169.     1993    Roca, J., and P.D. Wagner.  Principles and information content of the multiple inert gas elimination technique.  Thorax 49(8):815-824, 1993.

170.     1994    Rodriguez-Roisin, M.A. Felez, K. Fan Chung, J.A. Barberà, P.D. Wagner, A. Cobos, P.J. Barnes and J. Roca.  Platelet-activating factor causes ventilation/perfusion mismatch in humans.  J. Clin. Invest. 93(1):188-194, 1994.

171.     1994    Barbera, J.A., A. Riverola, J. Roca, J. Ramirez, P.D. Wagner, D. Ros, B.R. Wiggs, R. Rodriguez-Roisin.  Pulmonary vascular abnormalities and ventilation/perfusion relationships in mild COPD.  Am. J. Respir. Crit. Care Med.  149:423-429, 1994.

172.     1994    Kurdak, S.S., M.C. Hogan and P.D. Wagner.  Adenosine infusion does not improve maximal O₂ uptake in isolated working dog muscle.  J. Appl. Physiol. 76(6):2820-2824, 1994.

173.     1994    Erickson, B.K., J. Seaman, K. Kubo, A. Hiraga, M. Kai, Y. Yamaya, and P.D. Wagner.  Mechanism of reduction in alveolar-arterial Po₂ difference by helium breathing in the exercising horse.  J. Appl. Physiol. 76(6):2794-2801, 1994.

174.     1994    Agusti, AG.N., J. Roca, J.A. Barberá, J. Casademont, R. Rodriguez-Roisin and P.D. Wagner.  Effect of sampling site on femoral venous blood gas values.  J. Appl. Physiol. 77(4):2018-2022, 1994.

175.     1994    Gonzalez, N.C., L.P. Erwig, C.F. Painter, R.L. Clancy and P.D. Wagner.  Effect of hematocrit on systemic oxygen transport during hypoxic and normoxic exercise in rats.  J. Appl. Physiol. 77(3):1341-1348, 1994.

176.     1994    Wagner, P.D.  Determinants of maximum O₂ utilization.  Proc. 12th ACVIM Forum, ppg. 721-726, 1994.

177.     1995    Wagner, P.D.  Muscle O₂ transport and O₂ dependent control of metabolism.  Med. Sci. Sport Exerc. 27(1):47-53, 1995.

178.     1995    Seaman, J., B.K. Erickson, K. Kubo, A. Hiraga, M. Kai, Y. Yamaya and P.D. Wagner.  Exercise-induced ventilation/perfusion inequality in the horse.  Eq. Vet. J.  27(2):104-109, 1995.

179.     1995    Richardson, R.S., D.R. Knight, D.C. Poole, S.S. Kurdak, M.C. Hogan, B. Grassi and P.D. Wagner.  Determinants of maximal exercise V^. o₂ during single leg knee-extensor exercise in humans.  Am. J. Physiol. 268(37):H1453-H1461, 1995.

180.     1995    Wagner, P.D., B.K. Erickson, K. Kubo, A. Hiraga, M. Kai, Y. Yamaya, R.S. Richardson, and J. Seaman.  Maximum O₂ transport and utilization before and after splenectomy.  Eq. Vet. J. 18(Suppl):82-89, 1995.

181.     1995    Wagner, P.D.  Limitations of oxygen transport to the cell.  Intensive Care J. 21(5):391-398, 1995.

182.     1995    Erickson, B.K., J. Seaman, K. Kubo, A. Hiraga, M. Kai, Y. Yamaya, P.D. Wagner.  Hypoxic helium breathing does not reduce alveolar-arterial Po₂ difference in the horse.  Respir. Physiol., 100(3):253-260, 1995.

183.     1995    Nyman, G., M. Björk, P. Funkquist, S.G.B. Persson and P.D. Wagner.  Ventilation/perfusion relationships during graded exercise in the Standardbred trotter.  Eq. Vet. J. 18(Suppl):63-69, 1995.

184.     1995    Essén-Gustavsson, B., G. Nyman and P.D. Wagner.  Muscle and blood metabolic responses to intense exercise during acute hypoxia and hyperoxia.  Eq. Vet. J. 18(Suppl):181-187, 1995.

185.     1995    Bylin, G., L. Lagerstrand, G. Hedenstierna, P.D. Wagner.  Variability in airway conductance and lung volume in subjects with asthma.  Clin. Physiology, 15(3):207-218, 1995.

186.     1995    Richardson, R.S., E.A. Noyszewski, K.F. Kendrick, J.S. Leigh and P.D. Wagner.  Myoglobin O₂ desaturation during exercise: evidence of limited O₂ transport.  J. Clin. Invest. 96(4):1916-1926, 1995.

187.     1995    Richardson, R.S., B. Kennedy, D.R. Knight and P.D. Wagner.  High muscle blood flows are not attenuated by recruitment of additional muscle mass.  Am. J. Phys. 269 (38):H1545-H1552, 1995.

188.     1995    Johnson E.C., Erickson B.K., Podolsky A., Birks E.K., Keipert P.E., Faithfull N.S. and Wagner P.D.  Effects of a perfluorocarbon emulsion for enhanced oxygen solubility on hemodynamics and oxygen transport in dogs.  J. Appl. Physiol. 79(5):1777-1786, 1995.

189.     1995    Poole, D.C., P.D. Wagner and D.F. Wilson.  Diaphragm microvascular plasma Po₂ measured in vivo.  J. Appl. Physiol. 79(6):2050-2057, 1995.

190.     1995    Wagner, P.D.  Determinants of V^. o₂max:  Man vs. Horse.  J. Eq. Vet. Sci. 15(9):398-404, 1995.

191.     1995    Kurdak, S.S., B. Grassi, P.D. Wagner and M.C. Hogan.  Effect of [Hb] on blood flow distribution and O₂ transport in maximally working skeletal muscle.  J. Appl. Physiol., 79(5):1729-1735, 1995.

192.     1996    Grassi, B., D.C. Poole, R.S. Richardson, D.R. Knight, B.K. Erickson and P.D. Wagner.  Muscle O₂ uptake kinetics in humans: implications for metabolic control.  J. Appl. Physiol. 80(3):988-998, 1996.

193.     1996    Marrades, R.M., J. Roca, J. Campistol, O. Diaz, J.A. Barbera, J.V. Torregrosa, J.R. Masclans, A. Cobos, R. Rodriguez-Roisin and P.D. Wagner.  Effects of erythropoietin on muscle O₂ transport during exercise in patients with chronic renal failure.  J. Clin. Invest.   97(9):2092-2100, 1996.

194.     1996    Marrades, R.M., J. Alonso, J. Roca, J. Gonzalez de Suso, J. Campistol, J.A. Barberá, O. Diaz, J.V. Torregrosa, J.R. Masclans, R. Rodriguez-Roisin and P.D. Wagner.  Cellular bioenergetics after erythropoietin therapy in chronic renal failure.  J. Clin. Invest.  97(9):2101-2110, 1996.

195.     1996    Kurdak, S.S., B. Grassi, P.D. Wagner and M.C. Hogan.  Blood flow distribution in working in situ canine muscle during blood flow reduction.  J. Appl. Physiol. 80(6):1978-1983, 1996.

196.     1996    Knight, D.R., D.C. Poole, M.C. Hogan, D.E. Bebout and P.D. Wagner.  The effect of inspired O₂ concentration on leg lactate release during incremental exercise.  J. Appl. Physiol. 81(1):246-251, 1996.

197.     1996    Breen, E.C., E.C. Johnson, H. Wagner, H.-M. Tseng, L.A. Sung and P.D. Wagner.  Angiogenic growth factor mRNA responses in muscle to a single bout of exercise.  J. Appl. Physiol., 81(1):355-361, 1996.

198.     1996    Wagner, P.D., G. Hedenstierna and R. Rodriguez-Roisin.  Gas exchange, expiratory flow obstruction and the clinical spectrum of asthma.  Eur. Resp. J.  9(6):1278-1282, 1996.

199.     1996    Pappert, D., N. Gilliard, G. Heldt, T.A. Merritt, P.D. Wagner and R.G. Spragg.  Effect of n-nitroso-n-methylurethane on gas exchange, lung compliance, and surfactant function of rabbits.  Intensive Care Medicine 22(4):345-352, 1996.

200.     1996    Podolsky, A., M.W. Eldridge, R.S. Richardson, D.R. Knight, E.C. Johnson, S.R. Hopkins, D.H. Johnson, H. Michimata, B. Grassi, J. Feiner, S.S. Kurdak, P.E. Bickler, J.W. Severinghaus and P.D. Wagner.  Exercise-induced V^• a/ Q^•  inequality in subjects with prior high altitude pulmonary edema.  J. Appl. Physiol., 81(2):922-932, 1996.

201.     1996    Eldridge, M.W., A. Podolsky, R.S. Richardson, D.H. Johnson, D.R. Knight, E.C. Johnson, S.R. Hopkins, H. Michimata, B. Grassi, J. Feiner, S.S. Kurdak, P.E. Bickler, P.D. Wagner and J.W. Severinghaus.  Pulmonary hemodynamics response to exercise in subjects with prior high-altitude pulmonary edema.  J. Appl. Physiol., 81(2):911-921, 1996

202.     1996    Wagner, P.D., B.K. Erickson, J. Seaman, K. Kubo, A. Hiraga, M. Kai and Y. Yamaya.  Effects of altered Fi_o2 on maximum V^• o₂ in the horse.  Respir. Physiol., 105(1-2):123-134, 1996.

203.     1996    Wagner, P.D.  A theoretical analysis of factors determining V^• o₂max at sea level and altitude.  Resp. Physiol., 106(3):329-343, 1996.

204.     1996    Shimazu, T., T. Yukioka, H. Ikeuchi, A.D. Mason, Jr., P.D. Wagner and B.A. Pruitt, Jr.  Ventilation/perfusion alterations following smoke inhalation injury in an ovine model.  J. Appl. Physiol. 81(5):2250-2259, 1996.

205.     1996    Wagner, P.D.  Determinants of maximal oxygen transport and utilization.  Annu. Rev. Physiol. 58:21-50, 1996. (Invited Article)

206.     1996    Johnson, P.C., P.D. Wagner, D.F. Wilson.  Regulation of oxidative metabolism and blood flow in skeletal muscle.  Med. Sci. Sport Exerc. 28(3):305-314, 1996.

207.     1997    Wagner, P.D.  Insensitivity of V^• o₂max to hemoglobin – P₅₀ at sea level and altitude.  Respir. Physiol. 107(3):205-212, 1997.

208.     1997    Hopkins, S.R., E.C. Johnson, R.S. Richardson, H. Wagner, M. DeRosa and P.D. Wagner.  Effects of inhaled nitric oxide on gas exchange in lungs with shunt or poorly ventilated areas.  Am. J. Resp. Crit. Care Med.  156(2):484-491, 1997.

209.     1997    Cardús, J., F. Burgos, O. Diaz, J. Roca, J.A. Barberà, R.M. Marrades, R. Rodriguez-Roisin and P.D. Wagner.  Increase in pulmonary ventilation/perfusion inequality with age in healthy individuals.  Am. J. Resp. Crit. Care Med. 156(2):648-653, 1997.

210.     1997    Diaz, O., R. Iglesia, M. Ferrer, E. Zavala, C. Santos, P.D. Wagner, J. Roca and R. Rodriguez-Roisin.  Effects of noninvasive ventilation on pulmonary gas exchange during acute hypercapnic exacerbations of COPD. Am. J. Resp. Crit. Care Med. 156(6):1840-1845, 1997.

211.     1998    Richardson, R.S., K. Tagore, L. Haseler, M. Jordan and P.D. Wagner. Increased V^• o₂max with right shifted Hb-O₂ dissociation curve at a constant O₂ delivery in dog muscle in situ. J. Appl. Physiol. 84(3):995-1002, 1998. 

212.     1998    Hopkins, S.R., W.M. Bayly, R.F. Slocombe, H. Wagner and P.D. Wagner.  Effect of prolonged heavy exercise on pulmonary gas exchange in horses.  J. Appl. Physiol. 84(5):1723-1730, 1998. 

213.     1998    Cardus, J., R.M. Marrades, J. Roca, J.A. Barbera, O. Diaz, J.R. Masclans, R. Rodriguez-Roisin, P.D. Wagner.  Effects of Fi_o2  on leg V^. o₂ during cycle ergometry in sedentary subjects.  Med. Sci. Sports Exerc. 30(5):697-703, 1998. 

214.     1998    Richardson R.S., E.A. Noyszewski, J.S. Leigh, P.D. Wagner.  Lactate efflux from exercising human skeletal muscle: role of intracellular Po₂.  J. Appl. Physiol. 85(2):627-634, 1998.

215.     1998    Roca J., T. Gavin, M. Jordan, N. Siafakas, H. Wagner, H. Benoit, E. Breen and P.D. Wagner.  Angiogenic growth factor mRNA responses to passive and contraction-induced hyperperfusion in skeletal muscle.  J. Appl. Physiol. 85(3):1142-1149, 1998.

216.     1998    Hopkins, S.R., T.P. Gavin, N.M. Siafakas, L.J. Haseler, I.M. Olfert, H. Wagner, P.D. Wagner.  Effect of prolonged heavy exercise on pulmonary gas exchange in athletes.  J. Appl. Physiol. 85(4):1523-1532, 1998. 

217.     1998    Grassi, B., L.B. Gladden, C.M. Stary, P.D. Wagner, M.C. Hogan. Peripheral O₂ diffusion does not affect V^. o₂ on-kinetics in isolated in situ  canine muscle. J. Appl. Physiol. 85(4):1404-1412, 1998.

218.     1998    Richardson, R.S., B.T. Leek, P.D. Wagner, M. Kritchevsky.  Transient global amnesia:  A complication of incremental exercise testing. Med. Sci. Sports. Exerc. 30(10)(Suppl):S403-S405, 1998.

219.     1998    Ferrer, M., E. Zavala, O. Diaz, J. Roca, P.D. Wagner and R. Rodriguez-Roisin. Assessment of ventilation-perfusion mismatching in mechanically ventilated patients.  Eur. Resp. J. 12(5):1172-1176, 1998.

220.     1999    Richardson, R.S., B. Grassi, T.P. Gavin, L.J. Haseler, K. Tagore, J. Roca and P.D. Wagner.  Evidence of O₂ supply-dependent V^. o₂max in the exercise-trained human quadriceps. J. Appl. Physiol. 86(3):1048-1053, 1999.

221.     1999    Richardson, R.S., J. Sheldon, D.C. Poole, S.R. Hopkins, A.L. Ries, and P.D. Wagner. Evidence of skeletal muscle metabolic reserve during whole body exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 159(3):881-885, 1999. 

222.     1999    Hopkins, S.R., C.M. Stary, E. Falor, H. Wagner, P.D. Wagner and M.D. McKirnan. Pulmonary gas exchange during exercise in pigs.  J. Appl. Physiol. 86(1):93-100, 1999.

223.     1999    Benoit, H., M. Jordan, H. Wagner, and P.D. Wagner.  Effect of NO, vasodilator prostaglandins and adenosine on skeletal muscle angiogenic growth factor gene expression.  J. Appl. Physiol. 86(5):1513-1518, 1999.

224.     1999    Richardson, R.S., J.S Leigh, P.D. Wagner and E.A. Noyszewski.  Cellular Po₂ as a determinant of maximal mitochondrial O₂ consumption in trained human skeletal muscle.  J. Appl. Physiol. 87(1):325-331, 1999.

225.     1999    Sala, E., J. Roca, R.M. Marrades, J. Alonso, J.M. Gonzalez de Suso, A. Moreno, J.A. Barbera, J. Nadal, L. de Jover, R. Rodriguez-Roisin, and P.D. Wagner.  Effects of endurance training on skeletal muscle bioenergetics in chronic obstructive pulmonary disease.  Amer. J. Respir. Crit. Care Med. 159(6):1726-1734, 1999

226.     1999    Barker, R.C., S.R. Hopkins, N. Kellogg, I.M. Olfert, T.D. Brutsaert, T.P. Gavin, P.L. Entin, A.J. Rice, and P.D. Wagner.  Measurement of cardiac output during exercise by open-circuit acetylene uptake.  J. Appl. Physiol. 87(4):1506-1512, 1999.

227.     1999    Rice, A.J., A.T. Thornton, C.J. Gore, G.C. Scroop, H.W. Greville, H. Wagner, P.D. Wagner and S.R. Hopkins.  Pulmonary gas exchange during exercise in highly trained cyclists with arterial hypoxemia.  J. Appl. Physiol. 87(5):1802-1812, 1999.

228.     1999    Dempsey, J.A. and P.D. Wagner.  Exercise-induced arterial hypoxemia.  J. Appl. Physiol. 87(6):1997-2006, 1999.  (Invited Review)

229.     1999    Funkquist, P., P.D. Wagner, G. Hedenstierna, S.G.B. Persson, and G. Nyman.  Ventilation-perfusion relationships during exercise in Standardbred trotters with red cell hypervolaemia.  Equine Vet. J. 30(Suppl):107-113, 1999.

230.     1999    Richardson, R.S., H. Wagner, S.R.D. Mudaliar, R. Henry, E.A. Noyszewski and P.D. Wagner.  Human VEGF gene expression in skeletal muscle:  effect of acute normoxic and hypoxic exercise.   Amer. J. Physiol. 277 (Heart Circ Physiol 46):H2247-H2252, 1999.

231.     2000    Hepple, R.T., M.C. Hogan, C. Stary, D.E. Bebout, O. Mathieu-Costello and P.D. Wagner.   Structural basis of muscle O₂ diffusing capacity: evidence from muscle function in situ.   J. Appl. Physiol. 88(2):560-566, 2000.

232.     2000    Gavin, T.P., D.A. Spector, H. Wagner, E.C. Breen, and P.D. Wagner.  Nitric oxide synthase inhibition attenuates the skeletal muscle VEGF mRNA response to exercise.  J. Appl. Physiol. 88(4):1192-1198, 2000.

233.     2000    Gavin, T.P., D.A. Spector, H. Wagner, E.C. Breen, and P.D. Wagner.  Effect of captopril on skeletal muscle angiogenic growth factor responses to exercise.  J. Appl. Physiol. 88(5):1690-1697, 2000.

234.     2000    Hedenstierna, G., M. Hammond, Odile Mathieu-Costello, and P.D. Wagner.  Functional lung unit in the pig.  Respir. Physiol. 120(2):139-149, 2000.

235.     2000    Wagner, P.D.  Diffusive resistance to O₂ transport in muscle.  Acta Physiol. Scand. 168(4):609-614, 2000.

236.     2000    Wagner, P.D., C.C.W. Hsia, R. Goel, J.M. Fay, H.E. Wagner, and R.L. Johnson, Jr.  Effects of crocetin on pulmonary gas exchange in foxhounds during hypoxic exercise.  J. Appl. Physiol. 89(1):235-241, 2000.

237.     2000    Palange, P., and P.D. Wagner.  “The skeletal muscle in chronic respiratory diseases”, summary of the ERS Research Seminar in Rome, Italy, February 11-12, 1999. Eur. Resp. J. 15:807-815, 2000.

238.     2000    Richardson, R.S., H. Wagner, S.R.D. Mudaliar, E. Saucedo, R. Henry, and P.D. Wagner.  Exercise adaptation attenuates VEGF gene expression in human skeletal muscle.  Am. J. Physiol. (Heart Circ. Physiol.) 279(2):H772-H778, 2000. 

239.     2000    Hopkins, S.R., R.C. Barker, T.D. Brutsaert, T.P. Gavin, P. Entin, I.M. Olfert, S. Veisel and P.D. Wagner.  Pulmonary gas exchange during exercise in women: effects of exercise type and work increment. J. Appl. Physiol. 89(2):721-730, 2000.

240.     2000    Boushel, R.C., J.A.L. Calbet, G. Rådegran, H. Søndergaard, P.D. Wagner and B. Saltin.  Parasympathetic neural control of heart rate and cardiac output in chronic hypoxia.  Blood Gas News 9(2):14-17, 2000.

241.     2000    Spielvogel, H., M. Araoz and P.D. Wagner. Highlanders vs. acclimatized lowlanders.  Blood Gas News 9(2):18-23, 2000.

242.     2001    Sala, E., E.A. Noyszewski, J.M. Campistol, R.M. Marrades, S. Dreha, J.V. Torregrossa, J.S. Beers, P.D. Wagner and J. Roca.  Impaired muscle oxygen transfer in patients with chronic renal failure.  Am. J. Physiol. Regul. Integr. Comp. Physiol. 280: R1240-1248, 2001.

243.     2001    Gavin, T.P., P.D. Wagner.  Effect of short-term exercise training on angiogenic growth factor gene responses in rats.  J. Appl. Physiol. 90(4):1219-1226, 2001.

244.     2001    Olfert, I.M., E.C. Breen, O. Mathieu-Costello, and P.D. Wagner. Chronic hypoxia attenuates resting and exercise-induced VEGF, flt-1 and flk-1 mRNA levels in skeletal muscle.  J. Appl. Physiol. 90(4):1532-1538, 2001.

245.     2001    Siafakas, N.M., M. Jordan, H. Wagner, E.C. Breen, H. Benoit and P.D. Wagner.  Diaphragmatic angiogenic growth factor mRNA responses to increased ventilation caused by hypoxia and hypercapnia.  Eur. Resp. J. 17(4):681-687, 2001

246.     2001    Wagner, P.D., F. Masanes, H. Wagner, E. Sala, O. Miró, J.M. Campistol, R.M. Marrades, J. Casademont, V. Torregrosa and J. Roca.  Muscle angiogenic growth factor gene responses to exercise in chronic renal failure.  Am. J. Physiol. Regul. Integr. Comp. Physiol. 281:R539-546, 2001

247.     2001    Olfert, I.M., E.C. Breen, O. Mathieu-Costello and P.D. Wagner.  Skeletal muscle capillarity and angiogenic mRNA levels after exercise training in normoxia and chronic hypoxia.  J. Appl. Physiol. 91(3):1176-1184, 2001

248.     2001    Boushel, R., G. Rådegran, J.A.L. Calbet, H. Søndergaard, P.D. Wagner, and B. Saltin.  Parasympathetic neural activity accounts for the lowering of exercise heart rate at high altitude. Circulation 104(15):1785-1791, 2001

249.     2002    Yamaya, Y., H.J. Bogaard, P.D. Wagner, K. Niizeki, and S.R. Hopkins. Validity of pulse oximetry during maximal exercise in normoxia, hypoxia, and hyperoxia. J. Appl. Physiol. 92(1):162-168, 2002

250.     2002    Cremona, G.,  R. Asnaghi, P. Baderna, A. Brunetto, T. Brutsaert, C. Cavallaro, T.M. Clark, A. Cogo, R. Donis, P. Lanfranchi, A. Luks,  N. Novello, S. Panzetta, L. Perini, M. Putnam, L. Spagnolatti, H. Wagner and P.D. Wagner.   Pulmonary extravascular fluid accumulation in recreational climbers: a prospective study.  The Lancet 359(9303):303-309, 2002. 

251.     2002    Gavin, T.P. and P.D. Wagner.  Acute ethanol increases angiogenic growth factor gene expression in rat skeletal muscle.  J. Appl. Physiol. 92(3): 1176-1182, 2002

252.     2002    Wagner, P.D., M. Araoz, R. Boushel, J.A.L. Calbet, B. Jessen, G. Rådegran, H. Spielvogel, H. Søndegaard, H. Wagner and B. Saltin.  Pulmonary gas exchange and acid-base state at 5,260 m in high-altitude Bolivians and acclimatized lowlanders.  J. Appl. Physiol. 92(4):1393-1400, 2002

253.     2002    Bogaard, H.J., S.R. Hopkins, Y. Yamaya, K. Niizeki, M.G. Ziegler, and P.D. Wagner.  Role of the autonomic nervous system in the reduced maximal cardiac output at altitude. J. Appl. Physiol. 93(1):271-279, 2002

254.     2002    Gavin, T.P., and P.D. Wagner.  Attenuation of the exercise-induced increase in skeletal muscle Flt-1 mRNA by nitric oxide synthase inhibition.  Acta Physiol. Scand. 175(3):201-209, 2002

255.     2002    Brutsaert, T.D., T.P. Gavin, Z. Fu, E.C. Breen, K. Tang, O. Mathieu-Costello, and P.D. Wagner.  Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation.  BMC Physiology 2: 8, 2002

256.     2002    Henderson, K.K., H. Wagner, F. Favret, S.L. Britton, L.G. Koch, P.D. Wagner and N.C. Gonzalez.  Determinants of maximal O₂ uptake in rats selectively bred for endurance running capacity.  J. Appl. Physiol. 93(4):1265-1274, 2002

257.     2002    Yamaya, Y., K. Niizeki, J. Kim, P.L. Entin, H. Wagner and P.D. Wagner.  Effects of Optison on pulmonary gas exchange and hemodynamics.  Ultrasound Med. Biol. 28(8):1005-1013, 2002

258.     2002    Tang, K., E.C. Breen and P.D. Wagner. Hu Protein R-mediated posttranscriptional regulation of VEGF expression in rat gastrocnemius muscle.  Am. J. Physiol. Heart Circ. Physiol. 283(4):H1497-H1504, 2002

259.     2002    Calbet, J.A.L., G. Rådegran, R. Boushel, H. Søndergaard, B. Saltin and P.D. Wagner.  Effect of  blood haemoglobin on V^. o₂max and cardiovascular function in lowlanders acclimatized to 5260 m.  J. Physiology 545(2): 715-728, 2002

260.     2002    Bao, X., B.P. Kennedy, S.R. Hopkins, H.J. Bogaard, P.D. Wagner, M.G. Ziegler. Human autonomic activity and its response to acute oxygen supplement after high altitude acclimatization. Autonomic Neuroscience: Basic and Clinical. 102(1-2): 54-59, 2002.

261.     2002    Miro, O., R.M. Marrades, J. Roca, E. Sala, F. Masanes, J.M Campistol, J.V. Torregrosa, J. Casademont, P.D. Wagner and F. Cardellach.  Skeletal muscle mitochondrial function is preserved in young patients with chronic renal failure.  Am. J. Kidney Dis. 39(5):1025-1031, 2002. 

262.     2003    Calbet, J.A.L., R. Boushel, G. Rådegran, H. Søndergaard, P.D. Wagner and B. Saltin.  Determinants of maximal oxygen uptake in severe acute hypoxia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284(2):R291-R303, 2003. 

263.     2003    Calbet, J.A.L., R. Boushel, G. Rådegran, H. Søndergaard, P.D. Wagner and B. Saltin.  Why is V^.o₂max after altitude acclimatization still reduced despite normalization of arterial O₂ content?  Am. J. Physiol. Regul. Integr. Comp. Physiol. 284(2):R304-R316, 2003.

264.     2003    Howlett, R.A., N.C. Gonzalez, H.E. Wagner, Z. Fu, S.L. Britton, L.G. Koch, and P.D. Wagner.  Skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance.  J. Appl. Physiol. 94(4):1682-1688, 2003

265.     2003    Hepple, R.T., C.M. Stary, S. Kohin, P.D. Wagner and M.C. Hogan.  No effect of trans sodium crocetinate on maximal O₂ conductance or V^. o₂max in moderate hypoxia.  Respir. Physiol. Neurobiol. 134(3):239-246, 2003

266.     2003    Baum, M.M., S. Kumar, A.M. Lappas and P.D. Wagner.  Measurement of acetylene in breath by ultraviolet absorption spectroscopy:  Potential for noninvasive cardiac output monitoring.  Review of Scientific Instruments 74(6):3104-3110, 2003

267.     2003    Hopkins, S.R., H.J. Bogaard, K. Niizeki, Y. Yamaya, M.G. Ziegler, and P.D. Wagner.  b-adrenergic or parasympathetic inhibition, heart rate and cardiac output during normoxic and acute hypoxic exercise in humans.  J. Physiol. 550.2: 605-616, 2003

268.     2003    Hsia, C.C.W., R.L. Johnson, Jr., E.Y. Wu, A.S. Estrera, H. Wagner and P.D. Wagner.  Reducing lung strain after pneumonectomy impairs oxygen diffusing capacity but not ventilation-perfusion matching.  J. Appl. Physiol. 95(4):1370-1378, 2003

269.     2003    Pronk, M., I. Tiemessen, M.D.W. Hupperets, B.P. Kennedy, F.L. Powell, S.R. Hopkins, P.D. Wagner.  Persistence of the lactate paradox over 8 weeks at 3800 m.  High Alt. Med. Biol. 4(4): 431-443, 2003

270.     2004    Richardson, R.S., B.T. Leek, T.P. Gavin, L.J. Haseler, S.R.D. Mudaliar, R. Henry, O. Mathieu-Costello, P.D. Wagner.  Reduced mechanical efficiency in chronic obstructive pulmonary disease but normal peak V^. o₂ with small muscle mass exercise. Am. J. Respir. Crit. Care Med. 169(1): 89-96, 2004

271.     2004    Olfert, I.M., J. Balouch, A. Kleinsasser, A. Knapp, H. Wagner, P.D. Wagner and S.R. Hopkins.  Does gender affect human pulmonary gas exchange during exercise?  J. Physiol. 557(2): 529-541, 2004

272.     2004    Tang, K., E.C. Breen, H-P. Gerber, N.M.A. Ferrara, P.D. Wagner.  Capillary regression in vascular endothelial growth factor-deficient  skeletal muscle. Physiol. Genomics 18(1): 63-69, 2004

273.     2004    Baum, M.M., S. Kumar, J.A. Moss, P.D. Wagner.  Validation of a new spectrometer for noninvasive measurement of cardiac output.  Review of Scientific Instruments 75(7): 2290-2299, 2004

274.     2004    Tang, K., E.C. Breen, H. Wagner, T. Brutsaert, M. Gassmann and P.D. Wagner.  HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius.  Respir. Physiol. Neurobiol. 144(1): 71-80, 2004

275.     2004    Calbet J.A.L., Rådegran G., Boushel R., Søndergaard H., Saltin B. and P.D. Wagner.  Plasma volume expansion does not increase maximal cardiac output or VO₂max in lowlanders acclimatised to altitude.  Am. J. Physiol. Heart Circ. Physiol. 287(3): H1214-H1224, 2004

276.     2004    Hupperets, M.D.W., S.R. Hopkins, M.G. Pronk, I.J.H. Tiemessen, N. Garcia, P.D. Wagner and F.L. Powell.  Increased hypoxic ventilatory response during 8 weeks at 3,800 m altitude.  Respir. Physiol. Neurobiol. 142(2-3):145-152, 2004

277.     2004    Tang, K., H.B. Rossiter, P.D. Wagner, and E.C. Breen.  Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice.  J. Appl. Physiol. 97(4): 1559-1566, 2004

278.     2004    Mason, S.D., R.A. Howlett, M.J. Kim, I.M. Olfert, M.C. Hogan, W. McNulty, R.P. Hickey, P.D. Wagner, C.R. Kahn, F.J. Giordano, R.S. Johnson.  Loss of skeletal muscle HIF-1α results in altered exercise endurance.  PLoS Biology 2(10): 1540-1548, 2004

279.     2004    Yamaya, Y., K. Niizeki, J. Kim, P. Entin, H. Wagner, and P.D. Wagner.  Anaphylactoid response to Optison^Ò and its effects on pulmonary function in two dogs.  J. Vet. Med. Sci. 66(11): 1429-1432, 2004

280.     2005    Rossiter, H.B., R.A. Howlett, H.H. Holcombe, P.L. Entin, H. Wagner and P.D. Wagner.  Age is no barrier to muscle structural, biochemical and angiogenic adaptations to training up to 24 months in female rats.  J. Physiology, 565.3: 993-1005, 2005

281.     2005    Lanfranchi, P.A., R. Colombo, G. Cremona, P. Baderna, L. Spagnolatti, G. Mazzuero, P.D. Wagner, L. Perini, H. Wagner, C. Cavallaro, P. Giannuzzi.  Autonomic cardiovascular regulation in subjects with acute mountain sickness.  Am. J. Physiol. Heart Circ. Physiol. 289: H2364-H2372, 2005

282.     2006    Baum, M.M., J.A. Moss, S. Kumar, P.D. Wagner.  Non-invasive measurement of cardiac output: Evaluation of new infrared absorption spectrometer.  Respir. Physiol. Neurobiol. 153(2): 191-201, 2006

283.     2006    Vogiatzis, I., O. Georgiadou, I. Giannopoulou, M. Koskolou, S. Zakynthinos, K. Kostikas, E. Kosmas, H. Wagner, E. Peraki, A. Koutsoukou, N. Koulouris, P.D. Wagner, and C. Roussos. Effects of exercise-induced arterial hypoxaemia and work rate on diaphragmatic fatigue in highly trained endurance athletes.  J. Physiol, 572.2: 539-549, 2006.

284.     2006    Kirkton, S.D., H. Wagner, M.M. Landicho, J.J. Struthers, N. Busan, and P.D. Wagner.  Effects of Imagent^® on pulmonary hemodynamics and gas exchange in dogs.  Ultrasound Med. Biol., 32(6): 949-959, 2006.

285.     2006    Balouch, J., I.M. Olfert, P.D. Wagner, S.R. Hopkins.  The effect of incomplete acetylene washout on cardiac output measurement using open circuit acetylene uptake.  Respir Physiol Neurobiol, in press.

286.     2006    Heinicke, K., O. Baum, O.O. Ogunshola, J. Vogel, T. Stallmach, D.P. Wolfer, S. Keller, K. Weber, P.D. Wagner, M. Gassmann, V. Djonov.  Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal and muscular degeneration.  Am. J. Physiol. Regul. Integr. Comp. Physiol. 291: R_____-R_____, 2006

287.     2006    Gonzalez, N.C., S.D. Kirkton, R.A. Howlett, S.L. Britton, L.G. Koch, H.E. Wagner and P.D. Wagner.  Continued divergence in O_{2 max} of rats artificially selected for running endurance is mediated by greater convective blood O₂ delivery.  J. Appl. Physiol., in press 06/06

288.     2006    Olfert, I.M., E.C. Breen, T.P. Gavin and P.D. Wagner.  Temporal thrombospondin-1 mRNA response in skeletal muscle exposed to acute and chronic exercise  Growth Factors, in press 09/06

Book Chapters

1.         1977    Wagner, P.D.  Pulmonary gas exchange: Introduction.  In: Muscular Exercise and the Lung, chapt. 22, ed. J.A. Dempsey and C.E. Reed.  Univ. of Wisconsin Press, Madison, pp. 315-322.

2.         1977    West, J.B. and P.D. Wagner.              Pulmonary gas exchange.  In: Bioengineering Aspects of the Lung, chapt. 5, ed. J.B. West.  Marcel Dekker, New York, pp. 361-457.

3.         1977    Wagner, P.D.  Recent advances in pulmonary gas exchange.  In: International Anesthesiology Clinics, vol. 15.  Little, Brown & Co., Boston, pp. 81-111.

4.         1977    Wagner, P.D.  Ventilation/perfusion inequality and gas exchange during exercise in lung disease.  In: Muscular Exercise and the Lung, chapt. 24, ed. J.A. Dempsey and C.E. Reed.  Univ. of Wisconsin Press, Madison, pp. 345-356.

5.         1978    Wagner, P.D.  Measurement of the distribution of ventilation/perfusion ratios.  In: Research Topics in Physiology, vol. 1, Regulation of Ventilation and Gas  Exchange, chapt. 8, ed.  D.G. Davies and C. Barnes.  Academic Press, pp. 217-260.

6.         1979    Wagner, P.D. and J.B. West.              Changes in ventilation/perfusion relationships and gas exchange.  In: The Lung in Transition between Health and Disease, vol. 12, chapt. 8, ed. P.T. Macklem and S. Permutt.  Marcel Dekker, New York, pp. 183-226.

7.         1980    Wagner, P.D. and J.B. West.              Ventilation/perfusion relationships.  In: Pulmonary Gas Exchange, vol. 1, chapt. 7, ed. by J.B. West.   Academic Press, pp. 219-262.

8.         1980    Olszowka, A.J. and P.D. Wagner.  Numerical analysis in gas exchange.  In: Pulmonary Gas Exchange, vol. 1, chapt. 8, ed. J.B. West.  Academic Press, pp. 263-306.

9.         1982    Wagner, P.D.

                        Computing continuous distributions from limited data.  In: Computers in Critical Care and Pulmonary Medicine, vol. 2, ed. O. Prakash.  Plenum Press, New York/London, pp. 15-19.

10.       1982    Wagner, P.D.  Ventilation/perfusion inequality in catastrophic lung disease.  In: Applied Physiology in Clinical Respiratory Case, ed. O. Prakash.  Martinus Nijhoff, The Hague/Boston/London, pp. 363-379.

11.       1983    Wagner, P.D.  Expired gas measurements.  In: The Selective and Comprehensive Testing of Adult Pulmonary Function, ed. E. Leslie Chusid.  Futura Publishing Co., New York, pp. 137-172.

12.       1983    Wagner, P.D.  Mixed venous Po₂ (Pvo₂) and arterial Po₂, Pco₂, and pH.  In: The Selective and Comprehensive Testing of Adult Pulmonary Function, ed. E. Leslie Chusid.  Futura Publishing Co., New York, pp. 173-196.

13.       1983    Wagner, P.D.  Analysis of gas exchange in critically ill patients: implications of ventilation/perfusion mismatching.  In: Integrated Approaches to Monitoring, ed. J.S. Gravenstein, R.S. Newbower, A.K. Ream and N.T. Smith.  Butterworths, Walburn, pp. 97-109, chapt. 7.

14.       1984    Wagner, P.D. and F.A. Lopez.  Gas chromatography techniques in respiratory physiology.  In: Techniques in the Life Sciences, ed. A.B. Otis.  Elsevier Scientific Publishers Ireland Ltd., County Clare, Ireland, pp. 403/1-403/24.

15.       1984    Wagner, P.D. and R. Dueck.  Mechanisms of abnormal gas exchange during anesthesia.  In: International Journal of Clinical Monitoring and Computing, vol. 1, ed. O. Prakash.  Martinus Nijhoff Publishers, The Netherlands, pp. 59-71.

16.       1984    Wagner, P.D.  Gas exchange during conventional and high-frequency ventilation.  In: Critical Care of the Child, chapt. 13, ed. O. Prakash.  Martinus Publishers, The Netherlands, pp. 141-152.

17.       1986    Wagner, P.D.  Estimation of cardiac output and lung tissue volume in closed circuit (rebreathing) systems.  In: Closed-Circuit System and other Innovations in Anaesthesia, ed. R. Droh and R. Spintge.  Springer-Verlag, Berlin/Heidelberg, pp. 79-84.

18.       1986    Wagner, P.D.  Pulmonary gas exchange.  In: High Frequency Ventilation, chapt. 3, ed. L.H. Hamilton and J.M. Calkins.  CRC Press Inc., Florida, pp. 21-42. 

19.       1987    Wagner, P.D.  Peripheral inert-gas exchange.  In: Handbook of Physiology, chapt. 14, Section 3: The Respiratory System, vol. IV, ed. A.P. Fishman, L.E. Farhi, S.M. Tenney and S.R. Geiger.  American Physiological Society, pp. 257-281.

20.       1987    Wagner, P.D.  Respiratory gas exchange.  In: Handbook of Bioengineering, chapt. 26, ed. R. Skalak and S. Chien.  McGraw-Hill Book Co., New York, pp. 26.1-26.17. 

21.       1988    Wagner, P.D.  Diffusion, diffusing capacity, and chemical reactions.  In: Pulmonary Diseases and Disorders, chapt. 14, vol. 1, 2nd edition, ed. A.P. Fishman.  McGraw-Hill Book Co., New York, pp. 199-204.

22.       1988    Wagner, P.D. An integrated view of the determinants of maximum oxygen uptake.  In: Oxygen Transfer from Atmosphere to Tissues, vol. 227, ed. N.C. Gonzalez and M.R. Fedde.  Plenum Press, New York, pp. 245-256.

23.       1988    Wagner, P.D.  Pulmonary gas exchange during exercise at altitude.  In: Hypoxia: The Tolerable Limits, chapt. 11, ed. J.R. Sutton, C.S. Houston and G. Coates.  Benchmark Press Inc., Indianapolis, Indiana, pp. 133-151.

24.       1988    Sutton, J.R., J.T. Reeves, B.M. Groves, P.D. Wagner, A. Cymerman, P.M. Young, M.K. Malconian, P.B. Rock and C.S. Houston.  Exercise at extreme altitude: Operation Everest II.  In: Exercise Factors: Nerve and Muscle, ed. by P. Russo and R. Balnave.  Cumberland College Press, Lidcombe, Australia, pp. 13-19.

25.       1988    Wagner, P.D.  The determinants of V^. o₂max.  In:  Annals of Sports Medicine 4(4):196-212.  Oxford University Press.

26.       1988    Wagner, P.D.  Hypobaric effects on the pulmonary circulation and high altitude pulmonary edema.  In:  Pulmonary Vascular Physiology and Pathophysiology, chapt. 6, vol. 38, ed. E.K. Weir and J.T. Reeves.  Marcel Dekker, Inc., New York/Basel, pp. 173-198.

27.       1988    Groves, B.M., J.T. Reeves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K. Malconian, P.B. Rock, P.M. Young, and C.S. Houston.  Pulmonary hemodynamics with prolonged hypoxia.  In:  Hypoxia, The Tolerable Limits, ed. J.R. Sutton, C.S. Houston, and G. Coates.  Benchmark Press, Indianapolis, pp. 181-194.

28.       1988    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, A. Cymerman, M.K. Malconian, P.B. Rock, P.M. Young, J.K. Alexander, and C.S. Houston.  Cardiac function with prolonged hypoxia.  In:  Hypoxia, The Tolerable Limits, ed. J.R. Sutton, C.S. Houston, and G. Coates.  Benchmark Press, Indianapolis, pp. 195-206.

29.       1988    Reeves, J.T., B.M. Groves, P.D. Wagner, A. Cymerman, P.M. Young, P.B. Rock, M.K. Malconian, J.R. Sutton, H. Green, and C.S. Houston.  Operation Everest II:  maintained muscle energy stores during exercise at extreme altitude.  In:  High-Altitude Medical Science, ed. G. Ueda.  Shinshu University, matsumoto, Japan, pp. 3-12.

30.       1988    Sutton, J.R., J.T. Reeves, P.D. Wagner, A. Cymerman, M.K. Malconian, P.B. Rock, P.M. Young, and C.S. Houston.  Tolerable limits of hypoxia for the lungs: oxygen transport.  In:  Hypoxia, The Tolerable Limits, ed. J.R. Sutton, C.S. Houston, and G. Coates.  Benchmark Press, Indianapolis, pp. 123-132.

31.       1989    Romaldini, H. and P.D. Wagner.  Hemodialysis-induced respiratory distress.  In:  Treatment-Induced Respiratory Disorders, chapt. 25, vol. 3, ed. G.M. Akoun and J.P. White.  Elsevier Science Publishers, The Netherlands, pp. 340-347.

32.       1989    Wagner, P.D.  Summary - HFV and pulmonary physiology.  In:  Proceedings of International Symposium on High Frequency Ventilation, ed. P.P. Lunkenheimer, W.F. Whimster and M.K. Sykes.  January 29-30, Munster,  West Germany.  Acta Anaesthesiol. Scand. 32 (Suppl. 90):172-175.

33.       1989    Wagner, P.D.  Interpretation of conventional measurement of gas exchange in high frequency ventilation (HFV).  In:  Proceedings of International Symposium on High Frequency Ventilation, ed. P.P. Lunkenheimer, W.F. Whimster and M.K. Sykes.  January 29-30, Munster, West Germany.  Acta Anaethesiol. Scand. 33 (Suppl. 90):158-164.

34.       1990    Wagner, P.D.  A comparison of man and horse during heavy exercise.  In:  Hypoxia: The Adaptations, chapt. 24, ed. J.R. Sutton, G. Coates, and J.E. Remmers.  B.C. Decker Inc., Toronto/Philadelphia, pp. 142-147.

35.       1990    Huang, S-Y., P.R. Bender, B.M. Groves, R.E. McCullough, R.G. McCullough, A.J. Micco, M. Manco-Johnson, A.J. Hamilton, P.D. Wagner, A. Cymerman and J.T. Reeves.  Cerebral blood flow during exercise at sea level and at high altitude.  In:  Hypoxia: The Adaptations, chapt. 31, ed. J.R. Sutton, G. Coates and J.E. Remmers.  B.C. Decker Inc., Toronto/Philadelphia, pp. 196-199.

36.       1990    Johnson, R.L., Jr., C.C.W. Hsia, S.S. Cassidy, J.I. Carlin, P.D. Wagner and M. Ramanathan.  A post-pneumonectomy comparison of cardiac output and gas exchange in humans and dogs during heavy exercise.  In: Hypoxia: The Adaptations, chapt. 25, ed. J.R. Sutton, G. Coates and J.E. Remmers.  B.C. Decker Inc., Toronto/Philadelphia, pp. 148-154.

37.       1990    Roca, J., M. Hogan and P.D. Wagner.  Intercambio periferico de oxigeno.  In: Funcion Pulmonar en el Paciente Ventilado, chapt. 26, ed. A. Net and S. Benito.  DOYMA S.A., Barcelona, Spain, pp. 249-256.

38.       1990    Agusti, AGN, J. Roca, J. Bosch, P.D. Wagner, R. Mastai and R. Rodriguez-Roisin. The pulmonary circulation in cirrhosis.  In:  Recent Advances in the Pathophysiology and Therapy of Portal Hypertension, ed. J. Bosch and J. Rodes.  Serono Symposia Review No. 22, pp. 87-107.  3946.

39.       1991    Wagner, P.D., H. Hoppeler and B. Saltin. Determinants of maximal oxygen uptake.  In:  THE LUNG: Scientific Foundations, chapt. 5.6.3, ed. R.G. Crystal and  J.B. West et al.  Raven Press Ltd., New York, pp. 1585-1593 (revised 1994). (Invited Article)

40.       1991    Wagner, P.D.  Central and peripheral aspects of oxygen transport and adaptations with exercise.  Sports Medicine 11(3):133-142.  ADIS International, Auckland.

41.       1991    West, J.B., and P.D. Wagner.  Ventilation/perfusion relationships.  In:  THE LUNG: Scientific Foundations, chapt. 5.3.4, ed. R.G. Crystal and J.B. West et al.  Raven Press Ltd., New York, pp 1289-1305 (revised 1994, 1997). (Invited Article)

42.       1991    Wagner, P.D.  Effects of COPD on gas exchange.  In:  Chronic Obstructive Pulmonary Disease, chapt. 8, section III, ed. b N.S.  Cherniack.  W.B. Saunders Company, Philadelphia, pp. 73-79.

43.       1991    Wagner, P.D. and G.E. Gale.  Ventilation/perfusion relationships.  In: Exercise: Pulmonary Physiology and Pathophysiology, chapt. 4., ed. B.J. Whipp and K. Wasserman.  Marcel Dekker, Inc., New York/Basel, pp. 121-142.

44.       1991    Wagner, P.D.  The determinants of maximum oxygen utilization: The role of hemoglobin concentration.  In: Update in Intensive Care and Emergency Medicine, vol. 12, ed. G. Gutierrez and  J.L. Vincent.  Springer-Verlag, New York/Berlin, pp. 160-170.

45.       1991    Reeves, J.T., B.M. Groves, J.R. Sutton, P.D. Wagner, H.J. Green, A. Cymerman and C.S. Houston.  Adaptations to hypoxia: Lessons from Operation Everest II.  In: Current Pulmonology, chapt. 2, vol. 12, ed. D.H. Simmons.  Mosby Year Book, St. Louis, pp. 23-50.

46.       1991    Bebout, D.E., D. Story, J. Roca, M.C. Hogan, D.C. Poole, R. Gonzalez, O. Ueno, P. Haab and P.D. Wagner.  Pulmonary gas exchange during exercise following altitude acclimatization.  In:  Natural History of Eastern California and High Altitude Research.  White Mountain Research Station Symposium, Vol. 3. Eds. C.A. Hall, V. Doyle-Jones and B. Widawski.  Los Angeles, CA:  The Regents of The University of California, ppg. 336-338. (Invited Article)

47.       1992    Wagner, P.D.  Ventilation/perfusion inequality in Acute Respiratory Failure.  In: Adult Respiratory Distress Syndrome, chapt. 29, ed. A. Artigas, F. Lemaire, P.M. Suter and W.M. Zapol.  Churchill Livingstone, Edinburgh, London/Melbourne/New York, pp. 341-352. (Invited Article)

48.       1992    Wagner, P.D.  Adaptation of O₂ transport and utilization at altitude in man.  In: Oxygen Transport to Tissue XIV, Advances in Experimental Medicine and Biology, Vol 317, eds. W. Erdmann and D.F. Bruley.  Plenum Press, New York, pp. 75-94.

49.       1993    Wagner, P.D.  Heterogeneity, diffusion limitation and gas exchange.  In: Respiration in Health and Disease, Funktionsanalyse Biologischer Systeme, ed. P. Scheid.  Gustav Fischer, Stuttgart, New York.  pp. 23:121-127.

50.       1993    Wagner, P.D.  Pulmonary embolism and ARDS.  Journal of Clinical Respiratory Physiology, 25:127-150. (Invited Article)

51.       1994    Wagner, P.D. and P. Scheid.  Methods for measuring levels of O₂ in tissues.  In: Oxygen Transport to Tissue XVI.  Advances in Experimental Medicine and Biology, Vol. 361.  Eds. Hogan, M.C., O. Mathieu-Costello, D.C. Poole and P.D. Wagner.  Plenum Press, New York, pg. 371-374. (Invited Article)

52.       1994    Richardson, R.S., D.C. Poole, D.R. Knight and P.D. Wagner.  Red blood cell transit time in man:  theoretical effects of capillary density.  In:  Oxygen Transport to Tissue XVI. Advances in Experimental Medicine and Biology, Vol. 361.  Eds. Hogan, M.C., O. Mathieu-Costello, D.C. Poole and P.D. Wagner.  Plenum Press, New York, pp. 521-532. (Invited Article)

53.       1994    Hogan, M.C., S.S. Kurdak, R.S. Richardson and P.D. Wagner.  Partial substitution of red blood cells with free hemoglobin solution does not improve maximal O₂ uptake of working in situ muscle.  In: Oxygen Transport to Tissue XVI. Advances in Experimental Medicine and Biology, Vol. 361.  Eds. Hogan, M.C., O. Mathieu-Costello, D.C. Poole and P.D. Wagner.  Plenum Press, New York, pp. 375-378. (Invited Article)

54.       1994    Wagner, P.D.  Functional heterogeneity in the lungs.  In: Oxygen Transport to Tissue XVI. Advances in Experimental Medicine and Biology, Vol. 361.  Eds. Hogan, M.C., O. Mathieu-Costello, D.C. Poole and P.D. Wagner.  Plenum Press, New York, pp. 465. (Invited Article)

55.       1995    Wagner, P.D., M.W. Eldridge, A. Podolsky, R.S. Richardson, D.H. Johnson, D.R. Knight, E.C. Johnson, S.R. Hopkins, H. Michimata, B. Grassi, J. Feiner, S.S. Kurdak, P.E. Bickler and J.W. Severinghaus.  Elevated wedge pressure in HAPE-susceptible subjects during exercise.  Hypoxia and the Brain.  Eds. Sutton, J.R., C.S. Houston and G. Coates.  Queen City Printers, Inc., Burlington, VT., Chapter 21, pp. 251-264  (Invited Article)

56.       1996    Wagner, P.D.  Determinants of maximal oxygen transport and utilization.  Annual Review of Physiology, ed. D. Massaro, Annual Reviews, Inc., Palo Alto, CA, Chap. 9a, pp. 21-50. (Invited Article)

57.       1996    Wagner, P.D.  Pathophysiology of lung disease.  In:  Oxford Textbook of Medicine, 3rd Edition, Vol. 2, Chapter 17.4, eds. D.J. Weatherall, J.G.G. Ledingham and D.A. Warrell.  Oxford University Press, New York, ppg. 2628-2642. (Invited Article)

58.       1996    Johnson, P.C., P.D. Wagner and D.F. Wilson.  Regulation of oxidative metabolism and blood flow in skeletal muscle.  A summary report of the First ACSM Basic Science Specialty Conference, Indianapolis, IN  September 28-30, 1995.  Med. Sci. Sports Exerc., 28:305-314.

59.       1996    Handbook of Physiology.  Section 12:  Exercise:  Regulation and Integration of Multiple Systems.  Eds. L.B. Rowell and J.T. Shepherd. Assoc. Eds. J.A. Dempsey, J.M. Johnson, J.L. Smith, R. Terjung and P.D. Wagner.  Published for the American Physiological Society by Oxford University Press, New York.

60.       1996    Johnson, Jr., R.L., G.J.F. Heigenhauser, C.C.W. Hsia, N.L. Jones and P.D. Wagner.  Determinants of gas exchange and acid-base balance during exercise.  In: Handbook of Physiology.  Section 12:  Exercise:  Regulation and Integration of Multiple Systems, chapter 12, Eds. L.B. Rowell and J.T. Shepherd.  American Physiological Society by Oxford University Press, New York, ppg. 515-584.

61.       1997    Wagner, P.D.  Involvement of the lungs.  In:  Heart Failure:  Scientific Principles and Clinical Practice, chapter 17, eds. P.A. Poole-Wilson, W.S. Colucci, B.M. Massie, K. Chatterjee, A.J.S. Coats.  Churchill Livingstone, New York, ppg. 247-260.

62.       1997    Wagner, P.D.  Gas exchange.  In:  Asthma, Alan Leff, ed.  Raven Press, New York, pp. 1335-1347.

63.       1997    Wagner, P.D.  Ventilation, pulmonary blood flow, and ventilation/perfusion relationships.  In:  Pulmonary Diseases and Disorders, 3rd ed. Ed. Alfred P. Fishman, M.D.  Chapter XII, McGraw-Hill, Philadelphia, pp.177-192.

64. 1997    Roca, J., B.J. Whipp, A.G.N. Agusti, S.D. Anderson, R. Casaburi, J.E. Cotes, C.F. Donner, M. Estenne, H. Folgering, T.W. Higenbottam, K.J. Killian, P. Palange, A. Patessio, C. Prefaut, R. Sergysels, P.D. Wagner, I. Weisman.  ERS Task Force Review.  Clinical exercise testing with reference to lung diseases: indications, standardization and interpretation strategies.  In:  Eur Respir J 10:2662-2689. 

65.       1997    Whipp, B.J., P.D. Wagner, A. Agusti.  Factors determining the response to exercise in healthy subjects.  In:  ERS Monograph on Clinical Exercise Testing.  Eds. J. Roca, B. Whipp Sheffield, UK, Europ Respir J 2(Monograph 6):3-31.

66.       1997    Agusti, A.G.N., J. Cotes, P.D. Wagner.  Responses to exercise in lung diseases. In:  European Respiratory Monograph on Clinical Exercise Testing. Eds. J. Roca, B. Whipp, Sheffield, UK, Europ Respir J 2(Monograph 6):32-50.

67.       1997    Wagner, P.D., H. Hoppeler and B. Saltin.  Determinants of maximal oxygen uptake.  In:  THE LUNG: Scientific Foundations, 3^rd ed, chapt. 153, ed. R.G. Crystal and  J.B. West et al.  Raven Press Ltd., New York, pp. 2033-2041 (revised 1997).

68.       1998    Wagner, P.D.  The role of the cardiovascular system in coupling the external environment to cellular respiration.  In:  Cardiac Intensive Care, Ed. David L. Brown, Chapter 5, W.B. Saunders Co., Philadelphia, pp. 43-53.

69.       1998    West, J.B., P.D. Wagner.  Pulmonary gas exchange.  In:  Advances in Pulmonary Biology & Medicine.  Am. J. Respir. Crit Care Med (April 1998 supplement) 157(4):S82-S87.

70.       1998    Wagner, P.D.  Oxygen exchange in the lungs and muscles.  In:  1997 Nagano Symposium on Sports Sciences.  Ed. H. Nose, E.R. Nadel, T. Morimoto.  Chapter 1, Cooper Publishing Group, Indiana, pp. 3-20.

71.       1999    Casaburi, R., R. Gosselink, M. Decramer, P.N.R. Dekhuijzen, M. Fournier, M.I. Lewis, F. Maltais, D. Oelberg, M.B. Reid, J. Roca, A.M.W.J. Schols, G.C. Sieck, D. Systrom, P.D. Wagner, T.J. Williams, E.F.M. Wouters.  ATS Position Paper:  Skeletal muscle dysfunction in chronic obstructive pulmonary disease.  In:  Amer. J. Resp. Crit. Care Med. 159(4)(Part 2 of 2):S1-S40, 1999.

72.       1999    Roach, R.C., P.D. Wagner and P.H. Hackett (eds).  Hypoxia:  Into the Next Millennium.  In:  Advances in Experimental Medicine and Biology 474, Kluwer Academic/Plenum Publishers, New York, 1999. 

73.       2000    West, J.B., and P.D. Wagner.  Ventilation, blood flow and gas exchange.  In:  Textbook of Respiratory Medicine, 3^rd edition.  W.B. Saunders Co., Philadelphia; editors: Murray, J.F., and J.A. Nadel.  Chapter 4, pp. 55-89.

74.       2000    Pulmonary and Peripheral Gas Exchange in Health and Disease.  Editors: Roca, J., R. Rodriguez-Roisin and P.D. Wagner.  Marcel Dekker, New York.

75.       2000    Roca, J., R. Rodriguez-Roisin, P.D. Wagner.  Pulmonary and peripheral gas exchange and their interactions.  In:  Pulmonary and Peripheral Gas Exchange in Health and Disease.  Marcel Dekker, Inc., New York; editors: Roca, J., R. Rodriguez-Roisin and P.D. Wagner.  Chapter 1, pp. 1-25, 2000. 

76.       2000    Glenny, R., P.D. Wagner, J. Roca, and R. Rodriguez-Roisin.  Gas exchange in health:  Rest, exercise and aging.  In:  Pulmonary and Peripheral Gas Exchange in Health and Disease.  Marcel Dekker, Inc., New York; editors: Roca, J., R. Rodriguez-Roisin and P.D. Wagner.  Chapter 4, pp. 121-143, 2000.

77.       2000    Wagner, P.D.  New ideas on limitations to V^. o₂max .  Exerc. Sports Science Rev. 28(1):10-18, 2000   (Invited Article)

78.       2000    Williams, R.S., and P.D. Wagner.  Transgenic animals in integrative biology: approaches and interpretations of outcome.  J. Appl. Physiol. 88(3):1119-1126, 2000 (Invited Review)

79.       2000    Wagner, P.D.  Reduced maximal cardiac output at altitude—mechanisms and significance.  Respir. Physiol. 120(1): 1-11, 2000 (Invited Review)

80.       2001    Wagner, P.D.  Gas exchange.  In:  High Altitude:  An Exploration of Human Adaptation.  Marcel Dekker, Inc., New York; editors:  T.F. Hornbein and R.B. Schoene.  Chapter 8, pp. 199-234, 2001.  (36 pages)

81.       2001    Roach, R.C., P.D. Wagner and P.H. Hackett (eds).  Hypoxia: From Genes to the Bedside.  In:  Advances in Experimental Medicine and Biology 502.  Kluwer Academic/Plenum Publishers, New York, 2002. 

82.       2001    Wagner, P.D.  Skeletal muscle angiogenesis—a possible role for hypoxia.  In: Hypoxia: From Genes to the Bedside.  Kluwer Academic Plenum Press, New York; editors:  R. Roach, P.D. Wagner and P.H. Hackett.  Chapter 4, pp. 21-38, 2001 (18 pages) 

83.       2002    Wagner, H.E. and P.D. Wagner.  Performance of the GEM Premier 3000 at high altitude.  CriticIL Care News, Issue 5:5-7, October 2002

84.       2003    Weisman, I.M., K.C. Beck, R. Casaburi, J.E. Cotes, R.O. Crapo, J.A. Dempsey, M.S. Fairbarn, C.G. Gallagher, B.D. Johnson, K. Killian, D.A. Mahler, D.D. Marciniuk, F.J. Martinez, J. Myers, F.C. Sciurba, K.E. Sietsema, G.D. Swanson, D.Y. Sue, P.D. Wagner, B.J. Whipp, R.J. Zeballos.  ATS/ACCP Statement on cardiopulmonary exercise testing.  Am. J. Respir. Crit. Care Med. 167:211-277, 2003. 

85.       2003    Roach, R.C., P.D. Wagner and P.H. Hackett (editors).  Hypoxia Through the Lifecycle.  Advances in Experimental Medicine & Biology Volume 543, 2003.  Kluwer Academic Plenum Press, New York

86.       2003    Wagner, P.D.  Structure and function of the airways and alveoli. In:  Oxford Textbook of Medicine, 4^th edition.  New York:  Oxford University Press. D.A. Warrell, T.M. Cox, J.D. Firth, E.J. Benz, Jr., editors.  Chapter 17.1.2, pp. 1270-1277, 2003.

87.       2004    Rodriguez-Roisin, R., M.J. Krowka, P.H. Herve, M.B. Fallon on behalf of the PHD-ERS Task Force Scientific Committee. European Respiratory Society Task Force on Pulmonary-Hepatic Vascular Disorders (PHD) ERS Task Force.  Eur. Respir. J. 24(5): 861-880, 2004 (Invited Chapter)

88.       2005    Wagner, P.D.  Why doesn't exercise grow the lungs when other factors do?  Exercise & Sport Sciences Reviews 33(1): 3-8, 2005 (Book Chapter)

89.       2005    Wagner, P.D.  Section Head, Respiratory Physiology Section.  Faculty of 1000 Biology Reports Ltd.

90.       2005    Wagner, P.D. and J.B. West.  Ventilation, blood flow and gas exchange.  In:  Textbook of Respiratory Medicine, 4th edition, Chapter 4, pp. 51-86.  W.B. Saunders Co., Philadelphia; editors: Murray, J.F., and J.A. Nadel, 2005.

91.       2005    Wagner, P.D.  Ventilation/perfusion relationships.  In:  The Physiologic Basis of Respiratory Disease.  Hamic, Q., J. Shannon, J. Martin, editors.  Hamilton: BC Decker, Inc., 2005

92.       2006    Wagner, P.D.  The oxygen transport system: Integration of functions.  In:  ACSM's Advanced Exercise Physiology.  Lippincott-Williams & Wilkins, Philadelphia; editor, CM Tipton, Chapter 11, pp. 300-313, 2006

93.       2006    Wagner, P.D.  Peripheral gas exchange. In: Encyclopedia of Respiratory Medicine, pp. 316-323, GJ Laurent, SD Shapiro, editors; Oxford, UK: Elsevier Ltd., 2006

94.       2006    Wagner, P.D.  Ventilation, perfusion matching.  In: Encyclopedia of Respiratory Medicine, pp. 470-478, GJ Laurent, SD Shapiro, editors; Oxford, UK: Elsevier Ltd, 2006.

95.       2006    Hopkins, S.R. and P.D. Wagner, guest editors, Special Issue:  New Directions in Exercise Physiology.  In:  Respiratory Physiology & Neurobiology, 151 (2-3): 95-281, 2006.

96.       2006    Hopkins, S.R. and P.D. Wagner.  Foreword.  In:  Respiratory Physiology & Neurobiology, 151 (2-3): 95, 2006.

97.       2006    Gonzalez, N.C., R.A. Howlett, K.K. Henderson, L.G. Koch, S.L. Britton, H.E. Wagner, F. Favret, and P.D. Wagner. Systemic oxygen transport in rats artificially selected for running endurance.  In:  Respir Physiol Neurobiol., 151(2-3): 141-150, 2006 (Book Chapter). 
 
98.       2006    Wagner PD, I. Mark Olfert, K. Tang, E.C. Breen. Muscle-targeted deletion of VEGF and exercise capacity in mice.  In:  Respir Physiol Neurobiol., 151(2-3): 159-166, 2006 (Book Chapter). 

99.       2006    Wagner, P.D., E.C. Breen.  Angiogenesis—lessons learned from skeletal muscle.  In: Bronchial Vascular Remodeling in Asthma and COPD, Chap 9, pp. 197-212.  A. Lazaar, editor; New York: Informa Healthcare USA, Inc.  Lung Biology in Health and Disease, Vol 216, 2006

100.     2006    Wagner, P.D.  Pulmonary gas exchange.  In: Introduction to Bioengineering, in press, Shu Chien, editor.

101.     2006    Wagner, P.D.  The skeletal muscles in COPD: deconditioning, or myopathy?  Respirology 11(6):681-686, 2006 (Invited Review)

102.     2006    Wagner, P.D.  Ventilation, pulmonary blood flow and ventilation-perfusion relationships.  In:  Pulmonary Diseases and Disorders, Fourth Edition, A Fishman, AI Pack, editors. 

103.     2006    Roach, R.C., P.D. Wagner and P.H. Hackett (editors).  Hypoxia and Exercise.  Advances in Experimental Medicine & Biology Volume 588, 2006, Springer Press, Cambridge

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Last updated October 23, 2006.
©2006 Peter D. Wagner. All rights reserved.